E1279

Enoximone

solid

• Synonym(s): 1,3-Dihydro-4-methyl-5-(4-methylthiobenzoyl)-2H-imidazol-2-one
• Empirical Formula (Hill Notation): C₁₂H₁₂N₂O₂S
• CAS Number: 77671-31-9
• Molecular Weight: 248.30
• MDL number: MFCD00867130
• UNSPSC Code: 41106305
• PubChem Substance ID: 24278408
• NACRES: NA.77

Properties

• form: solid
• Quality Level: 100
• color: light yellow
• solubility: DMSO: soluble 28 mg/mL
• SMILES string: CSc1ccc(cc1)C(=O)C2=C(C)NC(=O)N2
• InChI: 1S/C12H12N2O2S/c1-7-10(14-12(16)13-7)11(15)8-3-5-9(17-2)6-4-8/h3-6H,1-2H3,(H2,13,14,16)
• InChI key: ZJKNESGOIKRXQY-UHFFFAOYSA-N
• Gene Information: human ... PDE3A(5139), PDE3B(5140)

Description

Biochem/physiol Actions

Selective phosphodiesterase III (PDE3) inhibitor. Prevents the degradation of cAMP by PDE.

Selective phosphodiesterase III (PDE3) inhibitor. Prevents the degradation of cAMP by PDE. Increased cAMP results in enhanced contractility of the heart.

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Phosphodiesterases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)