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EHU061411

Sigma-Aldrich

MISSION® esiRNA

targeting human PLXNB2

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51
Pricing and availability is not currently available.

description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

CTTCTTCCTGCCCTCCAAGGACGGCGACAAGGACGTGATGATCACCGGCAAGCTGGACATCCCTGAGCCGCGGCGGCCGGTGGTGGAGCAGGCCCTCTACCAGTTCTCCAACCTGCTGAACAGCAAGTCTTTCCTCATCAATTTCATCCACACCCTGGAGAACCAGCGGGAGTTCTCGGCCCGCGCCAAGGTCTACTTCGCGTCCCTGCTGACGGTGGCGCTGCACGGGAAACTGGAGTACTACACGGACATCATGCACACGCTCTTCCTGGAGCTCCTGGAGCAGTACGTGGTGGCCAAGAACCCCAAGCTGATGCTGCGCAGGTCTGAGACTGTGGTGGAGAGGATGCTGTCCAACTGGATGTCCATCTGCCTGTACCAGTACCTCAAGGACAGTGCCGGGGAGCCCCTGTACAAGCTCTTCAAGGCCATCAAACATCAGGTGGAAAAGGGCCCGGTGGATGCGGTACAGAAGAAGGC

Ensembl | human accession no.

ENSG00000196576

NCBI accession no.

NM_012401

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... PLXNB2(23654), PLXNB2(23654)

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Anti-MT5-MMP/MMP24 Antibody

Anti-DDX3 Antibody, clone AO196

MABE1921

Anti-DDX3 Antibody, clone AO196

Anti-REST Antibody, clone 12C11

MABE1982

Anti-REST Antibody, clone 12C11

Gene Information

mouse ... Junb(16477)

Gene Information

mouse ... Mmp24(17391)

Gene Information

human ... DDX3X(1654)

Gene Information

chicken ... REST(422623)

species reactivity

human, mouse

species reactivity

mouse, human

species reactivity

human

species reactivity

chicken, human, mouse

biological source

mouse

biological source

rat

biological source

mouse

biological source

mouse

antibody form

purified antibody

antibody form

purified antibody

antibody form

purified antibody

antibody form

purified antibody

clone

75-5, monoclonal

clone

3D2 also termed M24N 3D2, monoclonal

clone

AO196, monoclonal

clone

12C11, monoclonal

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

-

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

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    Brad McColl et al.
    Journal of cell science, 129(21), 4046-4056 (2016-11-03)
    Rnd proteins are atypical members of the Rho GTPase family that induce actin cytoskeletal reorganization and cell rounding. Rnd proteins have been reported to bind to the intracellular domain of several plexin receptors, but whether plexins contribute to the Rnd-induced
    Ying Zhang et al.
    Cellular signalling, 62, 109343-109343 (2019-06-10)
    Plexin-B2 (PLXNB2), a transmembrane protein is found in various tissues. Recent studies have indicated the presence of PLXNB2 in large quantity in the growth plates of Sprague-Dawley rats and are believed to be potentially involved in their skeletal development. This
    Audrey P Le et al.
    Oncotarget, 6(9), 7293-7304 (2015-03-13)
    Invasive growth is a major determinant of the high lethality of malignant gliomas. Plexin-B2, an axon guidance receptor important for mediating neural progenitor cell migration during development, is upregulated in gliomas, but its function therein remains poorly understood. Combining bioinformatic
    Daisuke Ito et al.
    Journal of immunology (Baltimore, Md. : 1950), 195(3), 934-943 (2015-06-28)
    Mammalian target of rapamycin (mTOR) plays crucial roles in activation and differentiation of diverse types of immune cells. Although several lines of evidence have demonstrated the importance of mTOR-mediated signals in CD4(+) T cell responses, the involvement of mTOR in

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