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EHU140561

Sigma-Aldrich

MISSION® esiRNA

targeting human IL6R

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

TCGGTGCCTTCCTCTTTTTATTTAGTTCCTTGAGTTGATTCAGCTCTGCAAGAATTGAAGCAGGACTAAATGTCTAGTTGTAACACCATGATTAACCACTTCAGCTGACTTTTCTGTCCGAGCTTTGAAAATTCAGTGGTGTTAGTGGTTACCCAGTTAGCTCTCAAGTTATCAGGGTATTCCAGAGTGGGGATATGATTTAAATCAGCCGTGTAACCATGGACCCAATATTTACCAGACCACAAAACTTTTCTAATACTCTACCCTCTTAGAAAAACCACCACCATCACCAGACAGGTGCGAAAGGATGAAAGTGACCATGTTTTGTTTACGGTTTTCCAGGTTTAAGCTGTTACTGTCTTCAGTAAGCCGTGATTTTCATTGCTGGGCTTGTCTGTAGA

Ensembl | human accession no.

ENSG00000160712

NCBI accession no.

NM_000565

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... IL6R(3570) , IL6R(3570)

General description

MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Wen Deng et al.
International journal of stem cells, 13(1), 142-150 (2020-01-01)
Mesenchymal stem cells (MSCs) have the multipotent capacity to differentiate into multiple tissue lineages as well as to self-renew, which is the main origin of adipocytes. IL6/IL6R pathway exerts a significant role in tissue regeneration and cell differentiation. Whereas, the
Xusheng Ding et al.
Cell death & disease, 9(9), 867-867 (2018-08-31)
Cancer-associated fibroblasts (CAFs) are important components of tumor stroma and play a key role in tumor progression. CAFs involve in crosstalk with tumor cells through various kinds of cytokines. In the present study, we screened hepatocyte growth factor (HGF) as
Arjan J van Adrichem et al.
FEBS letters, 589(24 Pt B), 3859-3865 (2015-11-26)
Male germ cell Rac GTPase-activating protein (MgcRacGAP) is a core regulator of cytokinesis. Furthermore, it appears to be involved in human oncogenesis through cytokinesis-independent mechanisms and has been reported to be essential for nuclear translocation of signal transducer and activator

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