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EHU158571

MISSION^® esiRNA

Name: MISSION<SUP>®</SUP> esiRNA
Brand: SIGMA

targeting human CTSE

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About This Item

UNSPSC Code:

41105324

NACRES:

NA.51

Pricing and availability is not currently available.

description

Quality Level

100

product line

MISSION^®

form

lyophilized powder

esiRNA cDNA target sequence

TCCTCTCTCCAGCTCCACATGCTGTACCTGGATCATTCTGAAGCAAATTCCGAGCATTACATCATTTTGTCCATAAATATTTCTAACATCCTTAAATATACAATCGGAATTCAAGCATCTCCCATTGTCCCACAAATGTTTGGCTGTTTTTGTAGTTGGATTGTTTGTATTAGGATTCAAGCAAGGCCCATATATTGCATTTATTTGAAATGTCTGTAAGTCTCTTTCCATCTACAGAGTTTAGCACATTTGAACGTTGCTGGTTGAAATCCCGAGGTGTCATTTGACATGGTTCTCTGAACTTATCTTTCCTATAAAATGGTAGTTAGATCTGGAGGTCTGATTTTGTGGCAAAAATACTTCCTAGGTGGTGCTGGGTACTTCTTGTTGCATCCTGTCAGG

Ensembl | human accession no.

ENSG00000196188

NCBI accession no.

NM_148964

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... CTSE(1510), CTSE(1510)

Related Categories

MISSION® esiRNA

Oligos, qPCR Probes & Peptides

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1 of 4

This Item	AB16955	SAB3500427	SAB1406725
$Anti-DR4 antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution$ SAB3500428 Anti-DR4 antibody produced in rabbit	AB16955 Anti-DR4 Antibody, CT	SAB3500427 Anti-DR5 antibody produced in rabbit	SAB1406725 Anti-TNFRSF10B antibody produced in mouse
conjugate unconjugated	conjugate -	conjugate unconjugated	conjugate unconjugated
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
antibody form IgG fraction of antiserum	antibody form affinity purified immunoglobulin	antibody form affinity isolated antibody	antibody form purified immunoglobulin
biological source rabbit	biological source rabbit	biological source rabbit	biological source mouse
clone polyclonal	clone polyclonal	clone polyclonal	clone polyclonal
storage temp. −20°C	storage temp. -	storage temp. −20°C	storage temp. −20°C

General description

MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Specification Sheet

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QCS

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The Critical Role of Proteolytic Relay through Cathepsins B and E in the Phenotypic Change of Microglia/Macrophage.

Junjun Ni et al.

The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(36), 12488-12501 (2015-09-12)

Proteinase cascades are part of the basic machinery of neuronal death pathways. Neuronal cathepsin B (CatB), a typical cysteine lysosomal protease, plays a critical role in neuronal death through lysosomal leakage or excessive autophagy. On the other hand, much attention

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