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EMU061331

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Irs1

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

TGACCTCAGCAAATCCTCCTTTTAACTCATGGGTACCCAGACTCGAACTATTTCACAATTCACAACCAGGACCTCACGTCTTCCTCTTCAGTAGATGGTACGATGCATCCGTTACAGTTTTGTTTACCTTGTACAATCCTCAGGAGTTCATTGACTGAACTGCACGTTGTACATTGTGCCAAGCAACAAGAAAGCACTGTGACACCGGAACAATTAGTGTGCATAAACTTCATCTTGAACTTTAAGGACAGCTGGTCACGAAGAGCTGGTGCACTTCCTACCACCAAGAGAATGGGTTTACTCTCATCAAATTTGCAACCGACGTTTCCTCTACTCTGAAACCGTGTTCCATGATGCGCCTCTGTAAATTACTCCATATGGAACTGTTCATGTTGGGTGGAGA

Ensembl | mouse accession no.

ENSMUSG00000055980

NCBI accession no.

NM_010570

shipped in

ambient

storage temp.

−20°C

Gene Information

mouse ... IRS1(16367) , Irs1(16367)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

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M Slevin et al.
Scientific reports, 5, 13281-13281 (2015-09-04)
Alzheimer's disease (AD) increases dramatically in patients with ischaemic stroke. Monomeric C-reactive protein (mCRP) appears in the ECM of ischaemic tissue after stroke, associating with microvasculature, neurons and AD-plaques, Aβ, also, being able to dissociate native-CRP into inflammatory, mCRP in
Kassondra Meyer et al.
Molecular and cellular biology, 35(17), 2991-3004 (2015-06-24)
Loss of repressor element 1 silencing transcription factor (REST) occurs in 20% of breast cancers and correlates with a poor patient prognosis. However, the molecular basis for enhanced malignancy in tumors lacking REST (RESTless) is only partially understood. We used

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