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EMU155981

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Nrxn3

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51
Pricing and availability is not currently available.

description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

AGAGTCTTTCCACTTCAATCTTCGAAGGTGGCTACAAAGCACATGCGCCCAAGTGGGAATCCAAGGACTTTAGACCTAACAAAGTCTCGGAAACTAGTAGAACTACAACCACCTCTTTGTCCCCTGAGCTGATCCGCTTCACAGCGTCCTCCTCGTCTGGGATGGTGCCCAAATTGCCAGCTGGCAAAATGAATAACCGTGATCTCAAACCCCAGCCTGATATAGTCTTGCTTCCGTTGCCCACTGCCTATGAGCTAGACAGCACCAAACTGAAGAGCCCACTAATTACTTCCCCCATGTTCCGTAATGTGCCCACAGCAAACCCCACGGAGCCAGGAATCAGACGGGTTCCGGGGGCCTCAGAGGTGATCCGGGAGTCCAGCAGTACAACAGGGATGGTCGTCGGCATTGTGGCTGCTGCCGCCCTCTGCATCTTGATCCTCCTGTACGCCATGTACAAGTACAGGAACAGGGACGAGGGGTCCTATCAAGTGGACGAGACGAGGAACT

Ensembl | mouse accession no.

ENSMUSG00000066392

NCBI accession no.

NM_172544

shipped in

ambient

storage temp.

−20°C

Gene Information

mouse ... NRXN3(18191), Nrxn3(18191)

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Julabo® CORIO™ C open heating bath circulator

material

stainless steel bath (Insulated)

material

stainless steel bath (Insulated)

material

stainless steel bath (Insulated)

capacity

14 L (19 L)

capacity

13 L (17 L)

capacity

17 L (27 L)

temperature measuring range

20-100 °C

temperature measuring range

20-100 °C

temperature measuring range

20-100 °C

external W × L × H

38 cm × 58 cm × 42 cm

external W × L × H

38 cm × 40 cm × 47 cm

external W × L × H

38 cm × 58 cm × 47 cm

manufacturer/tradename

Julabo 9011419

manufacturer/tradename

Julabo 9011417

manufacturer/tradename

Julabo 9011427

packaging

pack of 1 ea

packaging

pack of 1 ea

packaging

pack of 1 ea

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

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    Henry Beetham et al.
    Scientific reports, 9(1), 12511-12511 (2019-08-31)
    The cell-cell adhesion protein E-cadherin (CDH1) is a tumor suppressor that is required to maintain cell adhesion, cell polarity and cell survival signalling. Somatic mutations in CDH1 are common in diffuse gastric cancer (DGC) and lobular breast cancer (LBC). In
    Augustine Chen et al.
    BMC cancer, 14, 552-552 (2014-08-01)
    E-cadherin is an adherens junction protein that forms homophilic intercellular contacts in epithelial cells while also interacting with the intracellular cytoskeletal networks. It has roles including establishment and maintenance of cell polarity, differentiation, migration and signalling in cell proliferation pathways.
    Nicola Bougen-Zhukov et al.
    Cancers, 14(7) (2022-04-13)
    The CDH1 gene, encoding the cell adhesion protein E-cadherin, is one of the most frequently mutated genes in gastric cancer and inactivating germline CDH1 mutations are responsible for the cancer syndrome hereditary diffuse gastric cancer (HDGC). CDH1-deficient gastric cancers exhibit
    Lyvianne Decourtye-Espiard et al.
    Cancers, 14(1) (2022-01-12)
    Inactivating germline mutations in the CDH1 gene (encoding the E-cadherin protein) are the genetic hallmark of hereditary diffuse gastric cancer (HDGC), and somatic CDH1 mutations are an early event in the development of sporadic diffuse gastric cancer (DGC) and lobular

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