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G1029

Sigma-Aldrich

Monoclonal Anti-Granulocyte Colony Stimulating Factor antibody produced in mouse

clone 3316.111, purified immunoglobulin, lyophilized powder

Synonym(s):

Anti-G-CSF

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About This Item

MDL number:
UNSPSC Code:
12352203
NACRES:
NA.43
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biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

3316.111, monoclonal

form

lyophilized powder

species reactivity

human

technique(s)

capture ELISA: suitable
neutralization: suitable

isotype

IgG1

Immunogen

recombinant human granulocyte colony stimulating factor.

Biochem/physiol Actions

Mature myeloid cells are derived from bone-marrow derived precursor cells by the activity of three colony stimulating factors, granulocyte/macrophage colony-stimulating factor (GM-CSF), macrophage colony-stimulating factor (M-CSF) and granulocyte colony-stimulating factor (G-CSF). The expression of G-CSF is the result of activation of pathways in response to tumor necrosis factor-α, LPS and toll-like receptor ligands. The main functions of G-CSF include the generation of neutrophils and induction of the circulation of hematopoietic stem cells from the bone marrow.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.

Preparation Note

Purified using protein G.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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