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H2414

Sigma-Aldrich

Anti-Humanin (HN) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Humanin Detection Antibody, Rabbit Anti-Humanin

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About This Item

MDL number:
UNSPSC Code:
12352203
NACRES:
NA.41
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

western blot: 1:500

shipped in

dry ice

General description

Humanin (HN) is a small polypeptide, derived from mitochondria. This protein is secreted by various cells and is localized in the plasma and bound to the cell membranes.

Immunogen

peptide corresponding to the humanin protein (amino acids 9-24).

Application

Anti-Humanin (HN) antibody produced in rabbit has been used in:
  • immunohistochemistry
  • immunoprecipitation (1:300)
  • fluorescent immunohistochemistry (1:300)
  • immunoblotting (1:500)

Biochem/physiol Actions

Humanin (HN) acts as a neuroprotective factor. It is involved in promoting cell survival. Humanin suppresses cell death in the neuronal cells caused by Alzheimer′s disease-related insults like anti-amyloid- precursor protein antibody, neurotoxic amyloid β (Aβ) peptides, and familial Alzheimer disease proteins.

Physical form

Solution of 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


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