H6647

L-Histidinol dihydrochloride

≥98% (TLC)

• Synonym(s): β-Aminoimidazole-4-propanol dihydrochloride, (S)-2-Amino-3-(4-imidazolyl)propanol dihydrochloride
• Empirical Formula (Hill Notation): C₆H₁₁N₃O · 2HCl
• CAS Number: 1596-64-1
• Molecular Weight: 214.09
• Beilstein/REAXYS Number: 3914853
• EC Number: 216-482-2
• MDL number: MFCD00078058
• UNSPSC Code: 12352209
• PubChem Substance ID: 24895755
• NACRES: NA.32

Properties

• Product Name: L-Histidinol dihydrochloride, ≥98 (TLC)
• Quality Level: 200
• assay: ≥98% (TLC)
• form: powder
• color: white to off-white
• mp: 198-201 °C (dec.) (lit.)
• application(s): cell analysis
• SMILES string: Cl[H].Cl[H].N[C@H](CO)Cc1c[nH]cn1
• InChI: 1S/C6H11N3O.2ClH/c7-5(3-10)1-6-2-8-4-9-6;;/h2,4-5,10H,1,3,7H2,(H,8,9);2*1H/t5-;;/m0../s1
• InChI key: FRCAFNBBXRWXQA-XRIGFGBMSA-N
• Gene Information: human ... HRH1(3269) ; mouse ... HRH1(15465) ; rat ... HRH1(24448)

Description

Application

L-Histidinol dihydrochloride has been used:

• as a reagent in urinary metabolite analysis
• for making DT40 knockout cells, where cells were selected in 1mg/ml histidinol
• for inducing amino acid deprivation in HepG2 cells

Biochem/physiol Actions

Precursor of histamine; reversible inhibitor of protein synthesis.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves