I9759

Ile-Pro-Ile

≥97% (HPLC)

• Synonym(s): Diprotin A
• Empirical Formula (Hill Notation): C₁₇H₃₁N₃O₄
• CAS Number: 90614-48-5
• Molecular Weight: 341.45
• MDL number: MFCD00038707
• UNSPSC Code: 51111800
• PubChem Substance ID: 24896160
• NACRES: NA.77

Properties

• Quality Level: 200
• assay: ≥97% (HPLC)
• form: powder
• solubility: water: 1 mg/mL, clear, colorless
• storage temp.: −20°C
• SMILES string: CCC(C)C(N)C(=O)N1CCCC1C(=O)NC(C(C)CC)C(O)=O
• InChI: 1S/C17H31N3O4/c1-5-10(3)13(18)16(22)20-9-7-8-12(20)15(21)19-14(17(23)24)11(4)6-2/h10-14H,5-9,18H2,1-4H3,(H,19,21)(H,23,24)
• InChI key: JNTMAZFVYNDPLB-UHFFFAOYSA-N

Description

Amino Acid Sequence

Ile-Pro-Ile

Application

Ile-Pro-Ile has been used as a supplement for blood collection for hormone measurement and used in Islets cell culture to stabilize glucagon-like peptide-1 (GLP-1). It has also been used to inhibit the breakdown of gonadotropin-inhibitory hormone (GnIH) following serum collection.

Biochem/physiol Actions

Dipeptidyl peptidase IV Inhibitor. Inhibits entry of HIV-1 or HIV-2

Inhibitor of dipeptidyl peptidase IV. Inhibits entry of HIV-1 or HIV-2 into T lymphoblastoid and monocytoid cell lines.

Features and Benefits

This compound is featured on the Neuropeptidases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)