L6538

Limaprost

≥99%, crystalline

• Synonym(s): 11α,15S-Dihydroxy-17S,20-dimethyl-9-oxo-prosta-2E,13E-dien-1-oic acid, 17α,20-dimethyl-δ2-PGE1
• Empirical Formula (Hill Notation): C₂₂H₃₆O₅
• CAS Number: 74397-12-9
• Molecular Weight: 380.52
• MDL number: MFCD00868275
• UNSPSC Code: 51111800
• PubChem Substance ID: 329817640
• NACRES: NA.77

Properties

• Quality Level: 200
• assay: ≥99%
• form: crystalline
• solubility: DMF: soluble; DMSO: soluble; ethanol: soluble
• shipped in: wet ice
• storage temp.: −20°C
• SMILES string: CCCC[C@H](C)C[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCC\C=C\C(O)=O
• InChI: 1S/C22H36O5/c1-3-4-9-16(2)14-17(23)12-13-19-18(20(24)15-21(19)25)10-7-5-6-8-11-22(26)27/h8,11-13,16-19,21,23,25H,3-7,9-10,14-15H2,1-2H3,(H,26,27)/b11-8+,13-12+/t16-,17+,18+,19+,21+/m0/s1
• InChI key: OJZYRQPMEIEQFC-UAWLTFRCSA-N

Description

Biochem/physiol Actions

Limaprost exhibits cytoprotective, vasodilatory, and antiplatelet activity. Limaprost has the potential to treat lumbar spinal canal stenosis (LSCS) and several ischaemic symptoms of thromboangiitis obliterans (TAO).

Other Notes

Potent analog of PGE₁ with prolonged half-life.

Safety Information

• pictograms: GHS06
• signalword: Danger
• hcodes: H300
• pcodes: P264 - P301 + P310
• Hazard Classifications: Acute Tox. 2 Oral
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges