L6882

D-Luciferin sodium salt

luminescent, ≥98% (HPLC), lyophilized powder

• Synonym(s): (S)-2-(6-Hydroxy-2-benzothiazolyl)-2-thiazoline-4-carboxylic acid sodium salt, 4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic acid sodium salt, Firefly luciferin sodium salt
• Empirical Formula (Hill Notation): C₁₁H₇N₂NaO₃S₂
• CAS Number: 103404-75-7
• Molecular Weight: 302.30
• MDL number: MFCD00044938
• UNSPSC Code: 12352204
• PubChem Substance ID: 24896446
• NACRES: NA.32

Properties

• Product Name: D-Luciferin sodium salt, lyophilized powder, synthetic
• biological source: synthetic
• Quality Level: 200
• assay: ≥98% (HPLC)
• form: lyophilized powder
• solubility: H₂O: soluble
• fluorescence: λ_ex 328 nm; λ_em 532 nm in H₂O
• storage temp.: −20°C
• SMILES string: [Na+].Oc1ccc2nc(sc2c1)C3=N[C@H](CS3)C([O-])=O
• InChI: 1S/C11H8N2O3S2.Na/c14-5-1-2-6-8(3-5)18-10(12-6)9-13-7(4-17-9)11(15)16;/h1-3,7,14H,4H2,(H,15,16);/q;+1/p-1/t7-;/m1./s1
• InChI key: LILQLBIQROYWIA-OGFXRTJISA-M

Description

General description

D-Luciferin is mainly produced in bioluminescent organisms. It can simply circulate across the blood testis barrier, blood brain barrier and the blood placenta barrier. This small molecule is sensitive to light and oxygen. D-Luciferin is also sensitive to moisture in its powder form.

Application

D-Luciferin sodium salt has been used as a substrate in luciferin−luciferase chemiluminescence assay to determine ATP levels.

Substrate for firefly luciferase with a Km of approx 2 μM.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)