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M2140

Sigma-Aldrich

1-Decanoyl-rac-glycerol

≥99%

Synonym(s):

Monocaprin

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About This Item

Empirical Formula (Hill Notation):
C13H26O4
CAS Number:
2277-23-8
Molecular Weight:
246.34
EC Number:
247-667-6
MDL number:
MFCD00056656
UNSPSC Code:
12352211
PubChem Substance ID:
329817931
NACRES:
NA.25
Pricing and availability is not currently available.

biological source

synthetic (organic)

Quality Level

200

assay

≥99%

form

powder

functional group

ketone

lipid type

neutral glycerides

shipped in

ambient

storage temp.

−20°C

SMILES string

O=C(OCC(O)CO)CCCCCCCCC

InChI

1S/C13H26O4/c1-2-3-4-5-6-7-8-9-13(16)17-11-12(15)10-14/h12,14-15H,2-11H2,1H3

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2-(2H-Benzotriazol-2-yl)-4-methyl-6-(2-propenyl)phenol 99%

559857

2-(2H-Benzotriazol-2-yl)-4-methyl-6-(2-propenyl)phenol

2-(2H-Benzotriazol-2-yl)-4,6-bis(1-methyl-1-phenylethyl)phenol powder

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2-(2H-Benzotriazol-2-yl)-4,6-bis(1-methyl-1-phenylethyl)phenol

2-Hydrazinobenzothiazole 97%

642436

2-Hydrazinobenzothiazole

2-(2-Hydroxy-5-methylphenyl)benzotriazole certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

CRM96697

2-(2-Hydroxy-5-methylphenyl)benzotriazole

assay

99%

assay

-

assay

97%

assay

-

density

1.3 g/mL at 25 °C (lit.)

density

-

density

-

density

-

solubility

H2O: insoluble

solubility

H2O: insoluble <0.04 ppm at 20 °C, toluene: 20 wt. % at 20 °C, methylene chloride: 34 wt. % at 20 °C, chloroform: 35 wt. % at 20 °C

solubility

-

solubility

-

mp

98-101 °C (lit.)

mp

139-143 °C (lit.)

mp

198-202 °C (lit.)

mp

125.5-129.5 °C (lit.)

transition temp

transition temp >270 °C

transition temp

-

transition temp

-

transition temp

-

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

300

Application


  • Novel LC/MS/MS and High-Throughput Mass Spectrometric Assays for Monoacylglycerol Acyltransferase Inhibitors.: This research presents advanced assays for screening inhibitors of monoacylglycerol acyltransferase, with implications for metabolic disease treatment. 1-Decanoyl-rac-glycerol is a key compound in the study (Qi J et al., 2017).

  • Optimized reverse micelle surfactant system for high-resolution NMR spectroscopy of encapsulated proteins and nucleic acids dissolved in low viscosity fluids.: The paper describes a novel surfactant system using 1-Decanoyl-rac-glycerol, which improves the NMR spectroscopy of proteins and nucleic acids, offering better resolution and reduced viscosity (Dodevski I et al., 2014).

Biochem/physiol Actions

Monocaprin (glycerol monocaprate) is used in the development of antimicrobial disinfectants active against enveloped viruses, and certain yeast and bacteria such as candida albicans and campylobacter.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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    Certificates of Analysis (COA)

    Lot/Batch Number
    SLCM2543
    SLCG8550
    SLBT3218
    SLBQ6237V
    030M5222V

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    J R Brown et al.
    International journal of pharmaceutics, 245(1-2), 133-142 (2002-09-25)
    This study explores the potential of the monoglyceride monocaprin as an enhancer of the epithelial permeability of the beta(3)-adrenoceptor agonist BTA-243, as an approach to improving the bioavailability of this drug. The permeabilities of BTA-243 and mannitol (paracellular marker) in
    G Bergsson et al.
    APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 109(10), 670-678 (2002-03-14)
    The susceptibilities of three Gram-positive cocci to medium-chain saturated and long-chain unsaturated fatty acids and their one-monoglycerides were studied. The bacteria were incubated with equal volumes of lipid solutions for 10 min. Lauric acid, palmitoleic acid and monocaprin reduced the
    H Thormar et al.
    Letters in applied microbiology, 51(3), 319-324 (2010-07-30)
    Contamination in the kitchen with foodborne bacteria is a risk factor in human exposure to these pathogens, an important route being transfer of bacteria from contaminated cutting boards and other surfaces to humans. The aim of this study was to
    H Hilmarsson et al.
    Poultry science, 85(4), 588-592 (2006-04-18)
    Attempts have been made by several workers to prevent or to reduce colonization of Campylobacter in the intestines of broiler chickens by adding antibacterial agents to their food, but the results have varied. Monocaprin, the 1-monoglyceride of capric acid, has
    Thórunn O Thorgeirsdóttir et al.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 59(2), 333-342 (2005-01-22)
    The purpose of this study was to characterize the rheological and structural properties of a pharmaceutical multicomponent hydrogel formulation. This formulation consists of a hydrogel-forming poly(acrylic acid) polymer (Carbopol 974P), microbicide (monocaprin), non-ionic surfactant (Tween 20 or Tween 40), and
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