M2419

Midazolam maleate salt

≥98% (TLC), powder, GABAA receptor ligand

• Synonym(s): 8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine maleate salt
• Empirical Formula (Hill Notation): C₁₈H₁₃ClFN₃ · C₄H₄O₄
• CAS Number: 59467-94-6
• Molecular Weight: 441.84
• EC Number: 261-775-0
• MDL number: MFCD00941440
• UNSPSC Code: 12352200
• PubChem Substance ID: 24896731
• NACRES: NA.77

Properties

• Product Name: Midazolam maleate salt,
• Quality Level: 300
• drug control: USDEA Schedule IV; Home Office Schedule 3; psychotrope (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)
• originator: Roche
• storage temp.: 2-8°C
• SMILES string: OC(=O)\C=C/C(O)=O.Cc1ncc2CN=C(c3ccccc3F)c4cc(Cl)ccc4-n12
• InChI: 1S/C18H13ClFN3.C4H4O4/c1-11-21-9-13-10-22-18(14-4-2-3-5-16(14)20)15-8-12(19)6-7-17(15)23(11)13;5-3(6)1-2-4(7)8/h2-9H,10H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
• InChI key: XYGVIBXOJOOCFR-BTJKTKAUSA-N
• Gene Information: human ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562), GABRD(2563), GABRE(2564), GABRG1(2565), GABRG2(2566), GABRG3(2567), GABRP(2568), GABRQ(55879)

Description

Biochem/physiol Actions

Sedative/Hypnotic; ligand for the GABA_A receptor benzodiazepine modulatory site; CYP3A4 substrate.

Features and Benefits

This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves