Skip to Content
MilliporeSigma
All Photos(2)

Key Documents

View All Documentation

M5883

Sigma-Aldrich

7-Methylguanosine 5′-diphosphate sodium salt

≥92.5%

Synonym(s):

7-Methyl-gdp, m7GDP

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Empirical Formula (Hill Notation):
C11H17N5O11P2 · xNa+
CAS Number:
104809-16-7
Molecular Weight:
457.23 (free acid basis)
MDL number:
MFCD00057869
UNSPSC Code:
41106305
PubChem Substance ID:
329818024
NACRES:
NA.51
Pricing and availability is not currently available.

biological source

synthetic (organic)

Quality Level

200

assay

≥92.5%

form

powder

solubility

water: 50 mg/mL, clear to very slightly hazy, colorless to very faintly yellow

storage temp.

−20°C

SMILES string

[Na+].[Na+].C[n+]1cn([C@@H]2O[C@H](COP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]2O)c3nc(N)nc([O-])c13

InChI

1S/C11H17N5O11P2.2Na/c1-15-3-16(8-5(15)9(19)14-11(12)13-8)10-7(18)6(17)4(26-10)2-25-29(23,24)27-28(20,21)22;;/h3-4,6-7,10,17-18H,2H2,1H3,(H5-,12,13,14,19,20,21,22,23,24);;/q;2*+1/p-2/t4-,6-,7-,10-;;/m1../s1

InChI key

VSMXIKIFPKDZJA-IDIVVRGQSA-L

Related Categories

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
V8379SRP3186F0162
Vitronectin from rat plasma lyophilized powder, BioReagent, suitable for cell culture

V0132

Vitronectin from rat plasma

Vitronectin from human plasma lyophilized powder, BioReagent, suitable for cell culture

V8379

Vitronectin from human plasma

Vitronectin human recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture

SRP3186

Vitronectin human

Fibronectin Proteolytic Fragment from human plasma lyophilized powder, 45 kDa

F0162

Fibronectin Proteolytic Fragment from human plasma

biological source

rat plasma

biological source

human plasma

biological source

human

biological source

human plasma

Quality Level

200

Quality Level

300

Quality Level

200

Quality Level

200

form

lyophilized powder

form

lyophilized powder

form

lyophilized

form

lyophilized powder

mol wt

75 kDa

mol wt

A subunit 75 kDa, B subunit 65 kDa

mol wt

52.2 kDa (calculated)

mol wt

45 kDa

packaging

pkg of 50 μg

packaging

pkg of 50 μg

packaging

pkg of 250 μg

packaging

pkg of 0.5 mg

General description

7-Methylguanosine 5′-diphosphate (m7GDP) is derived when the human decapping Dcp2 enzyme cleaves the cap of the deadenylated mRNAs during the 5′–3′ mRNA decay pathway. [1]

Application

7-Methylguanosine 5′-diphosphate sodium salt has been used as a component of the elution buffer for the purification of 5’capped RNA.[2]

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

  • Specification Sheet

    • Choose from one of the most recent versions:

    Certificates of Analysis (COA)

    Lot/Batch Number
    SLCJ5789
    SLBQ2724V
    120M5071V
    SLBH3896V
    091M5051V

    Don't see the Right Version?

    If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

    Search for a COA

    Already Own This Product?

    Find documentation for the products that you have recently purchased in the Document Library.

    Visit the Document Library

    M Długosz et al.
    Journal of biochemical and biophysical methods, 51(2), 179-193 (2002-06-14)
    A method for extracting kinetic and optical parameters from progress curves for protein-ligand association, obtained by stopped-flow experiments, is described. The method is limited to one-step and two-step association kinetics, but it allows concentration of protein and offset of the
    Laurent Volpon et al.
    RNA (New York, N.Y.), 23(6), 927-937 (2017-03-23)
    The eukaryotic translation initiation factor eIF4E acts in the nuclear export and translation of a subset of mRNAs. Both of these functions contribute to its oncogenic potential. While the biochemical mechanisms that underlie translation are relatively well understood, the molecular
    Magdalena Lewdorowicz et al.
    RNA (New York, N.Y.), 10(9), 1469-1478 (2004-07-27)
    Leishmania and other trypanosomatids are early eukaryotes that possess unusual molecular features, including polycistronic transcription and trans-splicing of pre-mRNAs. The spliced leader RNA (SL RNA) is joined to the 5' end of all mRNAs, thus donating a 5' cap that
    Zhibo Zhang et al.
    Organic & biomolecular chemistry, 1(19), 3404-3409 (2003-10-31)
    The reactions of a 5'-cap model compound P1-(7-methylguanosine) P3-guanosine 5',5'-triphosphate, m7GpppG, were studied in the presence of three different macrocyclic amines (2-4) under neutral conditions. The only products observed in the absence of the macrocycles resulted from the base-catalysed imidazole
    Anna Wypijewska et al.
    Biochemistry, 51(40), 8003-8013 (2012-09-19)
    Decapping scavenger (DcpS) enzymes catalyze the cleavage of a residual cap structure following 3' → 5' mRNA decay. Some previous studies suggested that both m(7)GpppG and m(7)GDP were substrates for DcpS hydrolysis. Herein, we show that mononucleoside diphosphates, m(7)GDP (7-methylguanosine
    View All Related Papers

    Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

    Contact Technical Service