M7891

N-Methyl-N-(trimethylsilyl)trifluoroacetamide

BioReagent, for silylations, LiChropur^™

• Synonym(s): N-Trimethylsilyl-N-methyl trifluoroacetamide, MSTFA
• Linear Formula: CF₃CON(CH₃)Si(CH₃)₃
• CAS Number: 24589-78-4
• Molecular Weight: 199.25
• Beilstein/REAXYS Number: 1941550
• EC Number: 246-331-6
• MDL number: MFCD00000411
• UNSPSC Code: 12352111
• PubChem Substance ID: 57654411
• NACRES: NA.25

Properties

• vapor density: >1 (vs air)
• Quality Level: 100
• vapor pressure: 8.8 mmHg ( 27 °C)
• product line: BioReagent
• form: liquid
• quality: for silylations, LiChropur^™
• reaction suitability: reaction type: Silylations; reagent type: derivatization reagent
• technique(s): gas chromatography (GC): suitable
• refractive index: n20/D 1.38 (lit.)
• bp: 130-132 °C (lit.)
• solubility: chloroform: soluble 0.1 mg/mL
• density: 1.07 g/mL at 25 °C (lit.); 1.075 g/mL at 25 °C (lit.)
• storage temp.: 2-8°C
• SMILES string: CN(C(=O)C(F)(F)F)[Si](C)(C)C
• InChI: 1S/C6H12F3NOSi/c1-10(12(2,3)4)5(11)6(7,8)9/h1-4H3
• InChI key: MSPCIZMDDUQPGJ-UHFFFAOYSA-N

Description

General description

N-Methyl-N-(trimethylsilyl)trifluoroacetamide(MSTFA) is a BioReagent commonly used for silylation reactions in analyticalchemistry.

Application

N-Methyl-N-(trimethylsilyl)trifluoroacetamide can be used:

• In the derivatization step of the metabolomics analysis using gas chromatography/mass spectrometry (GC/MS).
• Derivatization reagent in gas chromatography with flame ionization detection (GC-FID) analysis.

Packaging

Sealed ampules contain 1 ml. Gram sizes are in screw-cap bottles.

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS02,GHS07
• signalword: Warning
• hcodes: H226,H315,H319,H335
• pcodes: P210 - P233 - P240 - P241 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: 77.0 °F - closed cup
• flash_point_c: 25 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter