N9407

Neuropeptide Y Fragment 3-36 human, rat

≥95% (HPLC)

• Synonym(s): NPY 3-36
• Empirical Formula (Hill Notation): C₁₇₅H₂₆₉N₅₃O₅₄S
• CAS Number: 150138-78-6
• Molecular Weight: 4011.40
• MDL number: MFCD00675824
• UNSPSC Code: 51111800
• NACRES: NA.32

Properties

• Quality Level: 200
• assay: ≥95% (HPLC)
• form: powder
• UniProt accession no.: P01303
• storage temp.: −20°C
• Gene Information: human ... NPY(4852)

Description

Amino Acid Sequence

Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH2

General description

Neuropeptide Y (NPY) is a regulatory protein consisting of 36 amino acids. It is ubiquitously expressed in the heart and brain. NPY is a member of pancreatic polypeptide family. The gene encoding this protein is localized on human chromosome 7p15.

Biochem/physiol Actions

Endogenous neuropeptide that selectively binds to Y<SUB>2</SUB> and Y<SUB>5</SUB> receptors.
Neuropeptide Y (NPY) plays a vital role in various processes like feeding behavior, anxiety, epilepsy, circadian rhythm, sleep, pain and drug addiction. It also modulates appetite, body weight and obesity. The protein has potent vasoactive effects on the cardiovascular system and controls central endocrine secretion. NPY is involved in the pathogenesis of atherosclerosis and coronary artery disease.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)