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Key Documents

O5507

Sigma-Aldrich

Linoleic acid, conjugated

Synonym(s):

CLA, Octadecadienoic acid, conjugated

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About This Item

UNSPSC Code:
12352211
NACRES:
NA.77

impurities

≤1% Linoleic acid

Quality Level

lipid type

omega FAs

storage temp.

−20°C

General description

A mixture of cis- and trans-9,11- and -10,12-octadecadienoic acids. Isomer ratio may vary from lot to lot.

Application


  • A targeted nanomodulator capable of manipulating tumor microenvironment against metastasis.: The paper discusses the development of a targeted nanomodulator, including conjugated linoleic acid, to manipulate the tumor microenvironment and inhibit metastasis. The findings suggest significant potential for improved cancer treatments (Tian et al., 2022).

  • Hyaluronic Acid-Modified Nanoparticles Self-Assembled from Linoleic Acid-Conjugated Chitosan for the Codelivery of miR34a and Doxorubicin in Resistant Breast Cancer.: The research focuses on hyaluronic acid-modified nanoparticles using linoleic acid-conjugated chitosan for the codelivery of miR34a and doxorubicin. This approach aims to overcome drug resistance in breast cancer treatments (Yang et al., 2022).

Biochem/physiol Actions

Potent inhibitor of breast, skin, and colon carcinogenesis and tumor cell proliferation; inhibits bFGF-induced endothelial cell proliferation; potent antioxidant.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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