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P2906

Sigma-Aldrich

Poly(ethylene glycol)

Hybri-Max™, mol wt 3,000-3,700, waxy solid, BioReagent, suitable for hybridoma

Synonym(s):

Polyethylene glycol, PEG

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About This Item

Linear Formula:
H(OCH2CH2)nOH
CAS Number:
25322-68-3
MDL number:
MFCD00081839
UNSPSC Code:
12161902
PubChem Substance ID:
24898372
NACRES:
NA.75
Pricing and availability is not currently available.

biological source

synthetic (organic)

Quality Level

200

grade

Hybri-Max™

sterility

autoclaved

product line

BioReagent

form

waxy solid

mol wt

3,000-3,700

technique(s)

cell culture | hybridoma: suitable

impurities

endotoxin, tested

SMILES string

C(CO)O

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1 of 4

This Item
1.725741.93698237205
Potassium hydrogen carbonate for analysis EMSURE® ACS

1.04854

Potassium hydrogen carbonate

Potassium hydrogen carbonate for table water, FCC, E 501

1.72574

Potassium hydrogen carbonate

Potassium hydrogen carbonate EMPLURA®

1.93698

Potassium hydrogen carbonate

Potassium bicarbonate ACS reagent, 99.7%, powder, crystals or granules

237205

Potassium bicarbonate

form

powder or crystals

form

powder

form

-

form

powder, crystals or granules

assay

≥99.5% (acidimetric), 99.7-100.5% dry basis (acidimetric)

assay

-

assay

-

assay

99.7%, 99.7-100.5% (ACS specification)

solubility

362 g/L

solubility

362 g/L

solubility

-

solubility

-

Quality Level

300

Quality Level

300

Quality Level

-

Quality Level

200

grade

ACS reagent

grade

-

grade

-

grade

ACS reagent

pH

8.4-8.6 (20 °C, 99 g/L in H2O)

pH

8.4-8.6 (20 °C, 99 g/L in H2O)

pH

-

pH

8.2 (10.01 g/L)

General description

Poly(ethylene glycol) (PEG) is a non-ionic hydrophilic polymer and is available in different molecular weights. It either exists in the form of a linear or branched structure. It aids in the purification and crystal growth of proteins and nucleic acids. PEG along with dextran is used to achieve an aqueous polymer two-phase system, which is essential for the purification of biological materials. It permits cell fusion through its interaction with the cell membrane.[1]

Application

Poly(ethylene glycol) has been used in the production of monoclonal antibodies.[2]
Recommended for cell fusion.

Legal Information

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

281.5 °F - closed cup

flash_point_c

138.6 °C - closed cup

ppe

Eyeshields, Gloves, type N95 (US)

  • Specification Sheet

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    Certificates of Analysis (COA)

    Lot/Batch Number
    SLBB2506V
    021M8722V
    021M8722
    060M8710
    088K8742

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    Extensive nuclear localization of alpha-synuclein in normal rat brain neurons revealed by a novel monoclonal antibody
    Yu S, et al.
    Neuroscience journal, 145(2), 539-555 (2007)
    Harris JM
    Poly(Ethylene Glycol) Chemistry: Biotechnical and Biomedical Applications (2013)
    Agathe Dubuisson et al.
    Cell death & disease, 10(2), 101-101 (2019-02-06)
    Development of therapeutic antibodies in oncology has attracted much interest in the past decades. More than 30 of them have been approved and are being used to treat patients suffering from cancer. Despite encouraging results, and albeit most clinical trials
    Idalis Villanueva et al.
    Acta biomaterialia, 5(8), 2832-2846 (2009-06-11)
    The pericellular matrix (PCM) surrounding chondrocytes is thought to play an important role in transmitting biochemical and biomechanical signals to the cells, which regulates many cellular functions including tissue homeostasis. To better understand chondrocytes interactions with their PCM, three-dimensional poly(ethylene
    Mark A Rice et al.
    Acta biomaterialia, 5(1), 152-161 (2008-09-17)
    Ultrasound has potential as a non-destructive analytical technique to provide real-time online assessments of matrix evolution in cell-hydrogel constructs used in tissue engineering. In these studies, chondrocytes were encapsulated in poly(ethylene glycol) hydrogels, and gel degradation was manipulated to provide
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