P3644
L-α-Phosphatidylcholine
from soybean, Type IV-S, ≥30% (enzymatic)
Synonym(s):
1,2-Diacyl-sn-glycero-3-phosphocholine, 3-sn-Phosphatidylcholine, L-α-Lecithin, Azolectin, PC
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About This Item
Recommended Products
biological source
soybean
Quality Level
type
Type IV-S
form
solid
concentration
≥30% (enzymatic)
solubility
chloroform: soluble 100 mg/mL, clear to slightly hazy, yellow to orange
functional group
phospholipid
lipid type
phosphoglycerides
shipped in
ambient
storage temp.
−20°C
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Application
L-α-Phosphatidylcholine is suitable for use:
- as a component of human erythroid massive amplification culture (HEMAdef) medium for clinical expansion of human erythroblasts
- in the chloride efflux assay to examine the chloride permeability of lipid vesicles conferred by soluble CLIC1
- in an assay to measure solubilized wax synthase activity
- as a component of buffer A used for the resuspension of the cholate-solubilized catalytic unit of adenylate cyclase
- as a cryoprotectant for freezing ruminant sperm
- as a substrate for the estimation of phospholipase activity
- to make liposomes to assess their efficiency of recruitment of ARF (ADP ribosylation factor) and AP-1 (adaptor protein)
- in the preparation of the isolated catalytic unit of soluble adenylate cyclase
Biochem/physiol Actions
A major structural phospholipid in brain, comprising approx. 15% of total lipid; primarily localized to gray matter.
Phosphatidylcholine is the major membrane phospholipid in eukaryotic cells, forming the structural component of these membranes. It also serves as a reservoir for several lipid messengers and a source for several bioactive lipids such as, lysophosphatidylcholine, phosphatidic acid, diacylglycerol, lysophosphatidylcholine, platelet activating factor, and arachidonic acid.
Preparation Note
Purified from P 5638
Storage Class
11 - Combustible Solids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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