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P6636

Sigma-Aldrich

L-α-Phosphatidylinositol from Glycine max (soybean)

~50% (TLC)

Synonym(s):

1,2-Diacyl-sn-glycero-3-phospho-(1-D-myo-inositol), Afamelanotide

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About This Item

CAS Number:
97281-52-2
Beilstein/REAXYS Number:
8535268
EC Number:
306-553-7
UNSPSC Code:
12352211
NACRES:
NA.25

biological source

soybean

Quality Level

200

form

crude powder

concentration

~50% (TLC)

functional group

phospholipid

lipid type

phosphoglycerides

shipped in

ambient

storage temp.

−20°C

SMILES string

CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)O[C@@H]1[C@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]1O)OC(=O)CCCCCCCCCCCCCCCCC

InChI

1S/C45H87O13P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-38(46)55-35-37(36-56-59(53,54)58-45-43(51)41(49)40(48)42(50)44(45)52)57-39(47)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h37,40-45,48-52H,3-36H2,1-2H3,(H,53,54)/t37-,40?,41-,42+,43-,44-,45?/m1/s1

InChI key

FQZQXPXKJFOAGE-KAEDGTSCSA-N

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Related Categories

Biochem/physiol Actions

Phospholipid membrane component, precursor of inositol phosphates.

Quality

May contain phosphatidic acid and phosphatidyl ethanolamine

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
SLCJ7229
SLCG1714
SLCC5135
SLBW3881
SLBV3296

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Lior Lobel et al.
Molecular microbiology, 95(4), 624-644 (2014-11-29)
Metabolic adaptations are critical to the ability of bacterial pathogens to grow within host cells and are normally preceded by sensing of host-specific metabolic signals, which in turn can influence the pathogen's virulence state. Previously, we reported that the intracellular
Qiangjun Zhou et al.
Nature communications, 5, 3552-3552 (2014-03-29)
Phosphatidylinositol 4-kinase IIα (PI4KIIα), a membrane-associated PI kinase, plays a central role in cell signalling and trafficking. Its kinase activity critically depends on palmitoylation of its cysteine-rich motif (-CCPCC-) and is modulated by the membrane environment. Lack of atomic structure
T Chakraborty et al.
Journal of bacteriology, 174(2), 568-574 (1992-01-01)
The prfA gene of Listeria monocytogenes encodes a protein that activates transcription of the listeriolysin gene (lisA). In order to explore the role of the prfA gene product in the pathogenesis of listerial infection, we constructed a site-directed insertion mutation
Tamar Burg-Golani et al.
Journal of bacteriology, 195(23), 5262-5272 (2013-09-24)
Listeria monocytogenes is a Gram-positive human intracellular pathogen that infects diverse mammalian cells. Upon invasion, L. monocytogenes secretes multiple virulence factors that target host cellular processes and promote infection. It has been presumed, but was not empirically established, that the
S H Notermans et al.
Applied and environmental microbiology, 57(9), 2666-2670 (1991-09-01)
In this study, 468 Listeria strains were checked for the presence of phosphatidylinositol-specific phospholipase C (PI-PLC) activity by using a simple assay that consisted of overlaying colonies formed on agar plates with L-alpha-phosphatidylinositol as substrate. In this assay, PI-PLC-active colonies
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