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P7643

Sigma-Aldrich

PIPES dipotassium salt

≥99% (titration)

Synonym(s):

1,4-Piperazinediethanesulfonic acid dipotassium salt, Piperazine-1,4-bis(2-ethanesulfonic acid) dipotassium salt

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About This Item

Empirical Formula (Hill Notation):
C8H16K2N2O6S2
CAS Number:
108321-27-3
Molecular Weight:
378.55
MDL number:
MFCD00069751
UNSPSC Code:
12161700
PubChem Substance ID:
24898738
NACRES:
NA.25
Pricing and availability is not currently available.

Quality Level

200

assay

≥99% (titration)

form

crystalline powder

useful pH range

6.1-7.5

pKa (25 °C)

6.8

solubility

water: 0.25 g/mL, clear, colorless

application(s)

diagnostic assay manufacturing

SMILES string

[K+].[K+].[O-]S(=O)(=O)CCN1CCN(CC1)CCS([O-])(=O)=O

InChI

1S/C8H18N2O6S2.2K/c11-17(12,13)7-5-9-1-2-10(4-3-9)6-8-18(14,15)16;;/h1-8H2,(H,11,12,13)(H,14,15,16);;/q;2*+1/p-2

InChI key

BJQYFCAMUXGZFN-UHFFFAOYSA-L

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material

borosilicate glass Type 1 , colorless tube, borosilicate glass tube

material

borosilicate glass Type 1 , borosilicate glass tube, colorless tube

material

borosilicate glass Type 1 , borosilicate glass tube, colorless tube

material

borosilicate glass Type 1 , borosilicate glass tube, colorless tube

parameter

600 MHz frequency

parameter

600 MHz frequency

parameter

300 MHz frequency

parameter

300 MHz frequency

feature

neck thread push fit

feature

neck thread push fit

feature

neck thread push fit

feature

neck thread push fit

concentricity × camber

13 μm × 6 μm

concentricity × camber

13 μm × 6 μm

concentricity × camber

51 μm × 13 μm

concentricity × camber

51 μm × 13 μm

tube diam. × L

5 mm × 7 in.

tube diam. × L

5 mm × 8 in.

tube diam. × L

-

tube diam. × L

-

wall thickness

0.38 mm

wall thickness

0.38 mm

wall thickness

0.43 mm

wall thickness

0.43 mm

General description

PIPES (1,4-Piperazinediethanesulfonic acid) is a zwitterionic buffer. It is a stable buffer and is used majorly in fixation solutions. PIPES is inert towards enzymatic and non-enzymatic reactions. However, it generates artefacts in transmission electron microscope imaging.[1]

Application

PIPES (1,4-Piperazinediethanesulfonic acid) dipotassium salt has been used as buffer for fluorescence polarization microscopy studies of kinesin-microtubule binding.[2] It is suitable for use as a component of PHEM buffer ([K-PIPES], HEPES, EGTA, and MgSO4) used during rinsing and blocking steps in immunofluorescence imaging of HeLa cells.[3] It is also suitable for use as buffer for purification of tubulin.[4]

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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    Certificates of Analysis (COA)

    Lot/Batch Number
    SLCH9283
    SLCD7100
    SLBV6424
    SLBR3825V
    030K5409V

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