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Key Documents

P9178

Sigma-Aldrich

Prochlorperazine dimaleate salt

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About This Item

Empirical Formula (Hill Notation):
C20H24ClN3S · 2C4H4O4
CAS Number:
Molecular Weight:
606.09
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.77

Pricing and availability is not currently available.

form

powder

Quality Level

solubility

H2O: slightly soluble 0.3 mg/mL
45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 2.3 mg/mL
methanol: soluble

originator

GlaxoSmithKline

SMILES string

OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.CN1CCN(CCCN2c3ccccc3Sc4ccc(Cl)cc24)CC1

InChI

1S/C20H24ClN3S.2C4H4O4/c1-22-11-13-23(14-12-22)9-4-10-24-17-5-2-3-6-19(17)25-20-8-7-16(21)15-18(20)24;2*5-3(6)1-2-4(7)8/h2-3,5-8,15H,4,9-14H2,1H3;2*1-2H,(H,5,6)(H,7,8)/b;2*2-1-

InChI key

DSKIOWHQLUWFLG-SPIKMXEPSA-N

Gene Information

human ... DRD2(1813)

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1 of 4

This Item
SAB4700109SAB4700112SAB4700113
biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

clone

LT19, monoclonal

clone

LT19, monoclonal

clone

LT19, monoclonal

clone

LT19, monoclonal

Gene Information

human ... CD19(930)

Gene Information

human ... CD19(930)

Gene Information

human ... CD19(930)

Gene Information

human ... CD19(930)

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

species reactivity

human

species reactivity

human

species reactivity

human

species reactivity

human

conjugate

Allophycocyanin conjugate

conjugate

unconjugated

conjugate

FITC conjugate

conjugate

phycoerythrin (R-PE) conjugate

Biochem/physiol Actions

Phenothiazine antipsychotic; D2 dopamine receptor antagonist; antispasmodic
Prochlorperazine is an anti-nausea and neuroleptic agent. It is known to cause neuropsychiatric side effects.[1] Prochlorperazine inhibits the action of dopamine in the central nervous system. It acts as an antiemetic drug and prevents vomiting and stimulates sleep. Prochlorperazine is useful as a tranquilizer in the treatment of schizophrenia and nonpsychotic anxiety.[2]

Features and Benefits

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

pictograms

Health hazardExclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Lact. - Repr. 2 - STOT SE 3

target_organs

Central nervous system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves


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