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PZ0150

Sigma-Aldrich

SU5614

≥98% (HPLC)

Synonym(s):

(3Z)-5-Chloro-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one

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About This Item

Empirical Formula (Hill Notation):
C15H13ClN2O
CAS Number:
Molecular Weight:
272.73
MDL number:
UNSPSC Code:
51111800
PubChem Substance ID:
NACRES:
NA.77
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Quality Level

assay

≥98% (HPLC)

form

powder

color

orange

solubility

DMSO: ≥20 mg/mL

storage temp.

2-8°C

SMILES string

Cc1cc(C)c(\C=C2/C(=O)Nc3ccc(Cl)cc23)[nH]1

InChI

1S/C15H13ClN2O/c1-8-5-9(2)17-14(8)7-12-11-6-10(16)3-4-13(11)18-15(12)19/h3-7,17H,1-2H3,(H,18,19)/b12-7-

InChI key

XLBQNZICMYZIQT-GHXNOFRVSA-N

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1 of 4

This Item
C-12217C-12219C-14020
biological source

human foreskin (juvenile dermis)

biological source

human dermis

biological source

human dermis

biological source

human foreskin (juvenile dermis)

morphology

( endothelial)

morphology

( endothelial)

morphology

( endothelial)

morphology

(endothelial)

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

-

packaging

pkg of 500,000 cells

packaging

pkg of 500,000 cells

packaging

pkg of 500,000 cells

packaging

pkg of 1,000,000 cells

storage temp.

−196°C

storage temp.

−196°C

storage temp.

room temp

storage temp.

−20°C

shipped in

dry ice

shipped in

dry ice

shipped in

ambient

shipped in

dry ice

Biochem/physiol Actions

SU5614 is a FMS-like tyrosine kinase 3 (FLT3) inhibitor.
SU5614 is a FMS-like tyrosine kinase 3 (FLT3) inhibitor; selective inhibitor of VEGF and PDGF receptor tyrosine kinases.

Features and Benefits

This compound is featured on the PDGFR page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

hcodes

Hazard Classifications

Aquatic Chronic 4

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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