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RAB0671

Sigma-Aldrich

Human GCG / Glucagon ELISA Kit

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About This Item

UNSPSC Code:
41116158
NACRES:
NA.32
Pricing and availability is not currently available.

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable

input

sample type plasma
sample type serum
sample type cell culture supernatant(s)

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 2.5 pg/mL
standard curve range: 2.03-130 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... GCG(2641)

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Anti-phospho-SHP-1 (pTyr564) antibody produced in rabbit affinity isolated antibody

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Anti-phospho-SHP-1 (pTyr564) antibody produced in rabbit

Anti-SHP-1 antibody produced in rabbit affinity isolated antibody

SAB4502529

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Anti-HIP14/ZDHHC17 antibody produced in goat affinity isolated antibody, buffered aqueous solution

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Anti-HIP14/ZDHHC17 antibody produced in goat

conjugate

unconjugated

conjugate

-

conjugate

unconjugated

conjugate

unconjugated

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

biological source

goat

biological source

rabbit

biological source

rabbit

biological source

goat

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

form

buffered aqueous solution

form

buffered aqueous solution

form

buffered aqueous solution

form

buffered aqueous solution

UniProt accession no.

P29350

UniProt accession no.

P29350

UniProt accession no.

P29350

UniProt accession no.

Q8IUH5

General description

Glucagon-like peptide-1 (GLP-1), a peptide hormone is liberated from endocrine epithelial cells of the small intestine.[1] The proglucagon gene (GCG) codes for glucagon, glucagon-like peptide-1 (GLP-1), and glucagon-like peptide-2 (GLP-2).[2]

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Glucagon-like peptide-1 (GLP-1) treatment helps to lower the risk of stroke in diabetic patients and to be neuroprotective in experimental stroke models.[1] It participates in glucose homeostasis and has an impact on the cardiovascular system.[3] GLP-1 may promote pancreatic β-cell proliferation and neogenesis. It enhances insulin release after a meal and triggers insulin transcription and biosynthesis.[2]

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Kit Components Also Available Separately

Product No.
Description
SDS
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)
  • RABSTOP3ELISA Stop Solution (Item I)
  • RABWASH420X Wash Buffer (Item B)

pictograms

Corrosion
GHS05

signalword

Warning

hcodes

H290

Hazard Classifications

Met. Corr. 1

Storage Class

8A - Combustible corrosive hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable

    • Choose from one of the most recent versions:

    Certificates of Analysis (COA)

    Lot/Batch Number
    1209I0037
    0705F0037
    0131F0037
    1019E0037
    0907D0037

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    Charles-Étienne Plourde et al.
    Obesity (Silver Spring, Md.), 22(8), 1838-1846 (2014-04-25)
    To assess the rapid improvement of insulin sensitivity and β-cell function following biliopancreatic diversion with duodenal switch (BPD-DS) and determine the role played by caloric restriction in these changes. Standard meals were administrated before and on day 3, 4, and
    Tianru Jin
    The Journal of endocrinology, 198(1), 17-28 (2008-06-26)
    The proglucagon gene (gcg) encodes a number of peptide hormones that are of cell-type specifically expressed in the pancreatic islets, the distal ileum and the large intestine, as well as certain brain neuronal cells. These hormones are important in controlling
    David R Powell et al.
    The Journal of pharmacology and experimental therapeutics, 350(2), 232-242 (2014-05-23)
    Treatments that lower blood glucose levels and body weight should benefit patients with type 2 diabetes mellitus (T2DM). We developed LX4211 [(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(methylthio)tetrahydro-2H-pyran-3,4,5-triol], an orally available small molecule that decreases postprandial glucose excursions by inhibiting intestinal sodium/glucose cotransporter 1 (SGLT1) and
    Benjamin B Albert et al.
    Scientific reports, 4, 6697-6697 (2014-10-22)
    We assessed whether omega-3 index (red blood cell concentrations of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)) was associated with insulin sensitivity and other metabolic outcomes in 47 overweight men aged 46.5 ± 5.1 years. Participants were assessed twice, 16
    Dongseong Shin et al.
    Clinical drug investigation, 34(6), 383-393 (2014-03-15)
    Gemigliptin is a novel dipeptidyl peptidase-4 (DPP-4) inhibitor used in the treatment of type 2 diabetes mellitus. This study evaluated possible pharmacodynamic and pharmacokinetic interactions between gemigliptin and metformin and investigated their tolerability. A randomized, open-label, multiple-dose, three-treatment, three-period, three-sequence
    View All Related Papers

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