Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

RAB0978

Sigma-Aldrich

Phosphotyrosine CSF1R / Macrophage Colony-stimulating Factor 1 Receptor ELISA Kit

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

UNSPSC Code:
41116158
NACRES:
NA.32
Pricing and availability is not currently available.

species reactivity

human

technique(s)

ELISA: suitable

assay range

inter-assay cv: <10%
intra-assay cv: <12%

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... CSF1R(1436)

Related Categories

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
RAB0961RAB0665RAB0098
Phosphotyrosine CSF1R / Macrophage Colony-stimulating Factor 1 Receptor ELISA Kit

RAB0978

Phosphotyrosine CSF1R / Macrophage Colony-stimulating Factor 1 Receptor ELISA Kit

Phosphotyrosine FGFR1 / Fibroblast Growth Factor Receptor 1 ELISA Kit

RAB0961

Phosphotyrosine FGFR1 / Fibroblast Growth Factor Receptor 1 ELISA Kit

Human CSF3R / Granulocyte Colony-Stimulating Factor Receptor ELISA Kit

RAB0665

Human CSF3R / Granulocyte Colony-Stimulating Factor Receptor ELISA Kit

Human M-CSF / CSF1 ELISA Kit for serum, plasma, cell culture supernatant, urine

RAB0098

Human M-CSF / CSF1 ELISA Kit

species reactivity

human

species reactivity

human

species reactivity

human

species reactivity

human

Gene Information

human ... CSF1R(1436)

Gene Information

human ... FGFR1(2260)

Gene Information

human ... CSF3R(1441)

Gene Information

human ... CSF1(1435)

assay range

inter-assay cv: <10%
intra-assay cv: <12%

assay range

inter-assay cv: <10%
intra-assay cv: <12%

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.1 ng/mL
standard curve range: 0.102-25 ng/mL

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 5 pg/mL
standard curve range: 2.78-2000 pg/mL

technique(s)

ELISA: suitable

technique(s)

ELISA: suitable

technique(s)

ELISA: suitable

technique(s)

ELISA: suitable, capture ELISA: suitable

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

General description

CSF1R (colony stimulating factor 1 receptor) or FMS, acts as a receptor for CSF1 and regulates monocyte and macrophage functioning. It is a member of the platelet-derived growth factor (PDGF) family of proteins and is a type III RTK (receptor tyrosine kinase). CSF1R is composed of five immunoglobulin (Ig)-like domains, a transmembrane region, a juxtamembrane domain and kinase insert domain (KID) intersecting the kinase domain.[1][2]
The antibody pair provided in this kit recognizes Human Tyrosine-Phosphorylated-MCSFR.

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

CSF1R (colony stimulating factor 1 receptor) and its ligand CSF1 are linked to poor prognosis in patients with solid tumors and in patients with female reproductive cancers. In breast cancers with decreased claudin levels, this protein regulates the switch between proliferative and invasive state of the tumor, acting downstream of TGFβ (tumor growth factor β). Haploinsufficiency in this receptor might lead to aberration of microglial function, which might be a contributor to the pathogenesis of hereditary diffuse leukoencephalopathy with spheroids (HDLS).[2][3][4]

Kit Components Also Available Separately

Product No.
Description
SDS
  • RABHRP6Phosphotyrosine ELISA HRP-Streptavidin

pictograms

Corrosion
GHS05

signalword

Warning

hcodes

H290

Hazard Classifications

Met. Corr. 1

Storage Class

8A - Combustible corrosive hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable

    • Choose from one of the most recent versions:

    Certificates of Analysis (COA)

    Lot/Batch Number

    It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

    If you need assistance, please contact Customer Support

    Already Own This Product?

    Find documentation for the products that you have recently purchased in the Document Library.

    Visit the Document Library

    Jan Leipert et al.
    Lab on a chip, 19(20), 3490-3498 (2019-09-19)
    While LC-MS-based proteomics with high nanograms to micrograms of total protein has become routine, the analysis of samples derived from low cell numbers is challenged by factors such as sample losses, or difficulties encountered with the manual manipulation of small
    Georg Michlits et al.
    Nature methods, 14(12), 1191-1197 (2017-10-19)
    Pooled CRISPR screens are a powerful tool for assessments of gene function. However, conventional analysis is based exclusively on the relative abundance of integrated single guide RNAs (sgRNAs) between populations, which does not discern distinct phenotypes and editing outcomes generated

    Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

    Contact Technical Service