RAB1754

Human Tryptase beta-2 ELISA

for serum, plasma and cell culture supernatants

• UNSPSC Code: 41116158
• NACRES: NA.32

Properties

• species reactivity: human
• packaging: kit of 96 wells (12 strips x 8 wells)
• technique(s): ELISA: suitable
• input: sample type serum; sample type cell culture supernatant(s); sample type plasma
• assay range: inter-assay cv: <12%; intra-assay cv: <10%; sensitivity: 2 ng/mL; standard curve range: 2.048-500 ng/mL
• detection method: colorimetric
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... TPSB2(64499)

Description

General description

Tryptase β2 (TPSB2) gene codes for mast cell tryptase β2. It is expressed in whole blood by mast cells and their progenitors.[1] Mast cell βII-tryptase protein is a S1A protease.[2]

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

Biochem/physiol Actions

Tryptase β2 (TPSB2) can break down the large fibronectin substrate into multiple, smaller peptides ranging in size from approximately 30 to 50 kDa. It can also cleave fibrinogen. TPSB2 is associated with pathological inflammation.[2]

Other Notes

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

Safety Information

• pictograms: GHS05
• signalword: Warning
• hcodes: H290
• pcodes: P234 - P390
• Hazard Classifications: Met. Corr. 1
• Storage Class: 8A - Combustible corrosive hazardous materials
• flash_point_f: Not applicable
• flash_point_c: Not applicable