SAB1300556

Anti-NR6A1 (C-term) antibody produced in rabbit

Ig fraction of antiserum, buffered aqueous solution

• Synonym(s): Anti-GCNF, Anti-Germ cell nuclear factor, Anti-HGCNF, Anti-RTR, Retinoid receptor-related testis-specific receptor
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: Ig fraction of antiserum
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• species reactivity: human
• technique(s): indirect ELISA: 1:1000; western blot: 1:100-1:500
• NCBI accession no.: NP_201591
• UniProt accession no.: Q15406
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... NR6A1(2649)

Description

General description

NR6A1 has been shown to affect gene expression in embryogenesis and spermatogenesis and is essential for embryonic survival and normal development. Loss of NR6A1 causes embryonic lethality and disrupts normal somitogenesis as well as neural-tube and axis formation. NR6A1 binds as a homodimer to the DR0 DNA response element and has been shown to regulate transcription of genes including protamines 1 and 2 and Oct4. NR6A1 repression function has been shown to be mediated by interaction with the co-repressors N-COR and SMRT in the absence of ligand.

Immunogen

NR6A1 (NP_201591, 340-375)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human NR6A1.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable