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SAB1300813

Sigma-Aldrich

Anti-GUCY1B2 (N-term) antibody produced in rabbit

saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution

Synonym(s):

Anti-GCS-β-2, Anti-GUCY1B2, Anti-Guanylate cyclase soluble, β-2 chain

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

Pricing and availability is not currently available.

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

saturated ammonium sulfate (SAS) precipitated

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

immunohistochemistry: 1:50-1:100
indirect ELISA: 1:1000
western blot: 1:100-1:500

NCBI accession no.

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This Item
HPA020870SAB1300814SAB1300870
biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

Quality Level

200

Quality Level

100

Quality Level

200

Quality Level

100

antibody form

saturated ammonium sulfate (SAS) precipitated

antibody form

affinity isolated antibody

antibody form

saturated ammonium sulfate (SAS) precipitated

antibody form

saturated ammonium sulfate (SAS) precipitated

clone

polyclonal

clone

polyclonal

clone

polyclonal

clone

polyclonal

technique(s)

immunohistochemistry: 1:50-1:100, western blot: 1:100-1:500, indirect ELISA: 1:1000

technique(s)

immunoblotting: 0.04-0.4 μg/mL, immunohistochemistry: 1:20-1:50

technique(s)

immunohistochemistry: 1:50-1:100, indirect ELISA: 1:1000

technique(s)

immunohistochemistry: 1:50-1:100, indirect ELISA: 1:1000, western blot: 1:100-1:500

General description

Nitric oxide-sensitive guanylyl cyclase is a heterodimeric enzyme consisting of an alpha and a beta subunit. The enzyme converts GTP into the second messenger cGMP and plays a major role in the cardiovascular system as a receptor for nitric oxide. Unlike other guanylyl cyclases, GUCY1B2 contains an 86-amino acid C-terminal extension with a consensus sequence for isoprenylation/carboxymethylation.

Immunogen

GUCY1B2 (NP_004120, 73-111)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human GUCY1B2.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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Storage Class

10 - Combustible liquids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


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