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SAB1305552

Sigma-Aldrich

Anti-MAP1LC3A antibody

mouse monoclonal, 166AT1234

Synonym(s):

Autophagy-related protein LC3 A, Autophagy-related ubiquitin-like modifier LC3 A, MAP1 light chain 3-like protein 1, MAP1LC3A, Microtubule-associated proteins 1A/1B light chain 3A

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400 μL
₩791,802

₩791,802


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400 μL
₩791,802

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

₩791,802


Please contact Customer Service for Availability
A recombinant, preservative-free antibody is available for your target. Try ZRB1125

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Product Name

MONOCLONAL ANTI-LC3 (APG8) antibody produced in mouse, clone 166AT1234, IgG fraction of antiserum, buffered aqueous solution

biological source

mouse

Quality Level

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

166AT1234, monoclonal

form

buffered aqueous solution

mol wt

14272 Da

species reactivity

rat, mouse, human

technique(s)

immunofluorescence: 1:25
immunohistochemistry: 1:50-1:100
western blot: 1:1000

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This Item
SAB1306617SAB1305638L8793
biological source

mouse

biological source

rabbit

biological source

rabbit

biological source

rabbit

species reactivity

rat, mouse, human

species reactivity

human, mouse

species reactivity

human

species reactivity

mouse, human, rat

clone

166AT1234, monoclonal

clone

polyclonal

clone

polyclonal

clone

polyclonal

antibody form

IgG fraction of antiserum

antibody form

purified immunoglobulin

antibody form

IgG fraction of antiserum

antibody form

affinity isolated antibody

Gene Information

human ... MAP1LC3A(84557)

Gene Information

human ... MAP1LC3A(84557)

Gene Information

human ... MAP1LC3A(84557)

Gene Information

human ... MAP1LC3A(84557)
mouse ... Map1lc3a(66734)
rat ... Map1lc3a(362245)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

200

Physical form

Supplied in PBS with 0.09% (W/V) sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable


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We have reported that conventional protein kinase Cγ (cPKCγ)-modulated neuron-specific autophagy improved the neurological outcome of mice following ischemic stroke through the Akt-mechanistic target of rapamycin (mTOR) pathway. However, its detailed molecular mechanism remains unclear. In this study, primary cortical
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The sequential reactivation of mechanistic target of rapamycin (mTOR) inhibited autophagic flux in neurons exposed to oxygen-glucose deprivation/reperfusion (OGD/R), which was characterized by reduction of autophagosome formation and restriction of autolysosome degradation. However, its detailed molecular mechanism was still unknown.

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