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SAB1410579

Sigma-Aldrich

Anti-TBK1 antibody produced in rabbit

purified immunoglobulin, buffered aqueous solution

Synonym(s):

FLJ11330, NAK, T2K

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
Pricing and availability is not currently available.

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 83.6 kDa

species reactivity

human

technique(s)

western blot: 1 μg/mL

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1 of 4

This Item
EMU022951EMU026871EMU060271
MISSION® esiRNA targeting mouse Ldlr

EMU015661

MISSION® esiRNA

MISSION® esiRNA targeting mouse Ldhc

EMU022951

MISSION® esiRNA

MISSION® esiRNA targeting mouse Ldb1

EMU026871

MISSION® esiRNA

MISSION® esiRNA targeting mouse Lgtn

EMU060271

MISSION® esiRNA

esiRNA cDNA target sequence

GACACCAAGGGCGTAAAGAGGAGGACACTGTTCCAAGAGGCAGGGTCCAGACCCAGAGCCATCGTAGTGGACCCTGTGCATGGCTTCATGTACTGGACAGATTGGGGAACACCCGCCAAGATCAAGAAAGGGGGTTTGAATGGTGTGGACATCCACTCACTGGTGACCGAAAACATCCAGTGGCCAAATGGCATCACACTAGATCTTTCCAGTGGCCGTCTCTATTGGGTTGATTCCAAACTCCACTCTATCTCCAGCATCGATGTCAATGGGGGCAATCGGAAAACCATTTTGGAGGATGAGAACCGGCTGGCCCACCCCTTCTCCTTGGCCATCTATGAGGACAAAGTGTATTGGACAGATGTCATAAACGAAGCCATTTTCAGTGCCAATCGACTCACGGGTTCAGATGTGAATTTGGTGGCTGAAA

esiRNA cDNA target sequence

CAGTGTGCCCATATGGAGTGGTGTAAACGTTGCTGGCGTAACTCTGAAGTCACTGAACCCAGCAATAGGAACTGACTCAGATAAGGAACACTGGAAAAATGTTCACAAGCAGGTGGTGGAAGGCGGCTATGAGGTCCTTAACATGAAGGGCTATACCTCTTGGGCTATCGGGCTGTCTGTGACTGATCTGGCGCGATCCATCTTGAAGAATCTTAAGAGAGTGCATCCTGTTACCACGCTGGTTAAGGGCTTCCATGGGATAAAGGAAGAGGTCTTCCTCAGTATCCCTTGTGTCTTGGGACAAAGTGGTATCACAGACTTTGTGAAAGTCAACATGACCGCTGAGGAGGAGGGTCTCCTCAAGAAGAGTGCGGACACACTCTGGAATATGCAGAAGGATCTGCAGTTATAAACTCGCCACCTTCGACCGTGTGACAGATGCCTGATC

esiRNA cDNA target sequence

TGCTGACCATCACTTTCTGCTTGGAGGATGGACCAAAGAGATATACCATTGGCCGGACCCTGATACCACGCTACTTCCGAAGCATTTTTGAGGGGGGTGCCACAGAGCTGTACTACGTGCTCAAGCACCCCAAGGAGGCATTCCACAGCAACTTCGTGTCCCTCGACTGTGACCAGGGCAGCATGGTGACCCAGCACGGCAAACCCATGTTTACCCAGGTGTGTGTGGAAGGCCGGTTGTACCTGGAGTTCATGTTTGACGACATGATGCGGATAAAGACGTGGCACTTCAGCATCCGGCAACACAGAGAGCTCATCCCCAGAAGTATCCTGGCCATGCACGCCCAGGACCCCCAGATGCTGGATCAGCTGTCCAAAAACATTACCCGGTGTGGGCTGTCCAATTCCACTCTCAACTACCTCCGACTCTGTGTGATACTAGAGCCCATGCAGGAACTT

esiRNA cDNA target sequence

GCAGCCTGCCTACCAAGTAACATTTCCTGGCCAGGAACCCATTCTAAAGAAAGGGAAACTCTGTCCAATTGATATCACCCTTGCACTGAAGACCTATAATAAAAAGGTGACTGTGGTCCGGAACTTGGAGACCTATGGTCTAGATCCGTGCTCAGTGGCCGCCATTCTCCAGCAGCGATGTCAGGCAAGCACCATCGTCTCTCCTGCCCCTGGGGCCAAAGACAGTCTGCAGGTGCAGGTCCAGGGAAACCAGATCCACCACCTTGGCCAGCTACTGCTTGAAATCATGTGGTGAGCCCCGGCAGTGCCTGGAGCTCAGCGGTGCTGTGACAGGGATCCCCTTGCTTATAACTGTGCTGCAGGACTGTTGCCTGTATTGCAGATGGGAAAACTGAGGTCCA

Gene Information

mouse ... LDLR(16835), Ldlr(16835)

Gene Information

mouse ... LDHC(16833), Ldhc(16833)

Gene Information

mouse ... LDB1(16825), Ldb1(16825)

Gene Information

mouse ... LGTN(16865), Lgtn(16865)

Ensembl | mouse accession no.

ENSMUSG00000032193

Ensembl | mouse accession no.

ENSMUSG00000030851

Ensembl | mouse accession no.

ENSMUSG00000025223

Ensembl | mouse accession no.

ENSMUSG00000026427

product line

MISSION®

product line

MISSION®

product line

MISSION®

product line

MISSION®

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

NCBI accession no.

NM_010700

NCBI accession no.

NM_013580

NCBI accession no.

NM_010697

NCBI accession no.

NM_010709

General description

The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. For example, the protein can form a complex with the IKB protein TANK and TRAF2 and release the NFKB inhibition caused by TANK. (provided by RefSeq)

Immunogen

TBK1 (NP_037386.1, 1 a.a. ~ 729 a.a) full-length human protein.

Sequence
MQSTSNHLWLLSDILGQGATANVFRGRHKKTGDLFAIKVFNNISFLRPVDVQMREFEVLKKLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYLHPDMYERAVLRKDHQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITGKPSGAISGVQKAENGPIDWSGDMPVSCSLSRGLQVLLTPVLANILEADQEKCWGFDQFFAETSDILHRMVIHVFSLQQMTAHKIYIHSYNTATIFHELVYKQTKIISSNQELIYEGRRLVLEPGRLAQHFPKTTEENPIFVVSREPLNTIGLIYEKISLPKVHPRYDLDGDASMAKAITGVVCYACRIASTLLLYQELMRKGIRWLIELIKDDYNETVHKKTEVVITLDFCIRNIEKTVKVYEKLMKINLEAAELGEISDIHTKLLRLSSSQGTIETSLQDIDSRLSPGGSLADAWAHQEGTHPKDRNVEKLQVLLNCMTEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYHATKAMTHFTDECVKKYEAFLNKSEEWIRKMLHLRKQLLSLTNQCFDIEEEVSKYQEYTNELQETLPQKMFTASSGIKHTMTPIYPSSNTLVEMTLGMKKLKEEMEGVVKELAENNHILERFGSLTMDGGLRNVDCL

Physical form

Solution in phosphate buffered saline, pH 7.4

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

  • Specification Sheet

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    Certificates of Analysis (COA)

    Lot/Batch Number
    09110

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    Nobuhiko Kayagaki et al.
    Science (New York, N.Y.), 341(6151), 1246-1249 (2013-07-28)
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    The enterotoxin T (BcET) from Bacillus cereus can probably not contribute to food poisoning.
    Choma C and Granum PE
    FEMS Microbiology Letters, 217, 115-115 (2002)
    Nicholas F Wright et al.
    The Journal of comparative neurology, 521(13), 2966-2986 (2013-03-19)
    Many brain structures project to both the anteroventral thalamic nucleus and the anteromedial thalamic nucleus. In the present study, pairs of different tracers were placed into these two thalamic sites in the same rats to determine the extent to which
    Contribution of CXCL12 secretion to invasion of breast cancer cells.
    Boimel PJ et al.
    Breast Cancer Research, 14, R23-R23 (2012)
    Rapid Expansion of Human Epithelial Stem Cells Suitable for Airway Tissue Engineering.
    Butler CR et al.
    American Journal of Respiratory and Critical Care Medicine, 194, 156-156 (2016)
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