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Key Documents

SAB4300372

Sigma-Aldrich

Anti-EZR (Ab-353) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-CVIL antibody produced in rabbit, Anti-CVL antibody produced in rabbit, Anti-DKFZp762H157 antibody produced in rabbit, Anti-FLJ26216 antibody produced in rabbit, Anti-ezrin antibody produced in rabbit

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

~81 kDa

species reactivity

human

concentration

1 mg/mL

technique(s)

western blot: 1:500-1:1000

isotype

IgG

immunogen sequence

(Q-D-Y-E-E)

NCBI accession no.

NP_001104547.1

UniProt accession no.

P15311

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... EZR(7430)

Related Categories

Immunogen

Peptide sequence around aa. 351-355 (Q-D-Y-E-E), according to the protein EZR.

Features and Benefits

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Target description

Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
511721094

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Takuro Kobori et al.
Biological & pharmaceutical bulletin, 37(7), 1124-1131 (2014-07-06)
Previously, we reported that repeated oral administration of etoposide (ETP) increases P-glycoprotein (P-gp) expression in association with activation of ezrin/radixin/moesin (ERM) via Ras homolog gene family member A (RhoA)/Rho-associated coiled-coil containing protein kinase (ROCK) signaling in the small intestine. However
Anita A Wasik et al.
The American journal of pathology, 184(6), 1727-1739 (2014-04-15)
Diabetic nephropathy is a complication of diabetes and a major cause of end-stage renal disease. To characterize the early pathophysiological mechanisms leading to glomerular podocyte injury in diabetic nephropathy, we performed quantitative proteomic profiling of glomeruli isolated from rats with
Yosuke Matsumoto et al.
PloS one, 9(8), e105435-e105435 (2014-08-22)
Neuronal morphogenesis is implicated in neuronal function and development with rearrangement of cytoskeletal organization. Ezrin, a member of Ezrin/Radixin/Moesin (ERM) proteins links between membrane proteins and actin cytoskeleton, and contributes to maintenance of cellular function and morphology. In cultured hippocampal

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