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SAB4502446

Sigma-Aldrich

Anti-CXCR7 antibody produced in rabbit

affinity isolated antibody

Synonym(s):

CXCR-7, CXCR7, G-protein coupled receptor 159, G-protein coupled receptor RDC1, chemokine orphan receptor 1

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
Pricing and availability is not currently available.

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 41 kDa

species reactivity

rat, mouse, human

concentration

~1 mg/mL

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assay

95%

assay

97%

assay

98%

assay

99%

Quality Level

100

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200

Quality Level

100

Quality Level

100

density

0.928 g/mL at 25 °C (lit.)

density

1.236 g/mL at 25 °C (lit.)

density

1.007 g/mL at 25 °C (lit.)

density

1.159 g/mL at 25 °C (lit.)

refractive index

n20/D 1.517 (lit.)

refractive index

n20/D 1.545 (lit.)

refractive index

n20/D 1.536 (lit.)

refractive index

n20/D 1.559 (lit.)

bp

140 °C/20 mmHg (lit.)

bp

93-94 °C/1.5 mmHg (lit.)

bp

135 °C/20 mmHg (lit.)

bp

168-169 °C/2 mmHg (lit.)

form

liquid

form

liquid

form

liquid

form

liquid

General description

Anti-CXCR7 Antibody detects endogenous levels of total CXCR7 protein.
CXC- Chemokine receptor 7 (CXCR7) protein is a seven-transmembrane G-protein coupled receptor (GPCR). It is expressed in the heart tissues, fetal hematopoietic cells, embryonic neuronal, and activated endothelium. CXCR7 gene is mapped on the human chromosome at 2q37.3.

Immunogen

The antiserum was produced against synthesized peptide derived from human CXCR7.

Immunogen Range: 311-360

Biochem/physiol Actions

CXC- Chemokine receptor 7 (CXCR7) protein interacts with chemokine ligands CXCL11 and CXCL12. This protein shuffles between the plasma membrane and endosomal compartments irrespective of the presence of a ligand such as CXCL11 and 12. CXCR7 protein plays a role in cell survival and cell adhesion to the endothelium. This protein tends to regulate the activity of CXCR4.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

  • Specification Sheet

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    Certificates of Analysis (COA)

    Lot/Batch Number
    61065

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