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Key Documents

SAB4504560

Sigma-Aldrich

Anti-phospho-Tau (pThr181) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-DDPAC, Anti-FTDP-17, Anti-MAPTL, Anti-MSTD, Anti-MTBT1, Anti-MTBT2, Anti-PPND, Anti-PPP1R103, Anti-TAU, Anti-tau-40

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
Pricing and availability is not currently available.

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 78 kDa

species reactivity

rat, human, mouse

concentration

~1 mg/mL

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Anti-Connexin 43 Antibody, CT Antibody, clone 1C5.1

clone

1C5.1, monoclonal

clone

polyclonal

clone

4E6.2, monoclonal

clone

1C5.1, monoclonal

conjugate

ALEXA FLUOR™ 488

conjugate

-

conjugate

-

conjugate

-

Gene Information

human ... GJA1(2697)

Gene Information

human ... GJA1(2697)

Gene Information

human ... GJA1(2697)

Gene Information

human ... GJA1(2697)

species reactivity

human, rat

species reactivity

human, rat, mouse

species reactivity

mouse, rat, pig, canine

species reactivity

rat, human

antibody form

purified antibody

antibody form

affinity isolated antibody

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

biological source

mouse

biological source

rabbit

biological source

mouse

biological source

mouse

General description

MAPT (microtubule associated protein tau) is located on human chromosome 17q21.3. This gene is expressed in neurons but is most prominent in axons.

Immunogen

The antiserum was produced against synthesized peptide derived from human Tau around the phosphorylation site of Thr181.

Immunogen Range: 471-520

Biochem/physiol Actions

MAPT (microtubule associated protein tau) participates in the pathology of Alzheimer′s disease (AD). It helps in the assembly and maintenance of microtubule structure. Removal of MAPT results in developmental delay and learning disability.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

  • Specification Sheet

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    Certificates of Analysis (COA)

    Lot/Batch Number
    117244

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    Already Own This Product?

    Find documentation for the products that you have recently purchased in the Document Library.

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    Microdeletion encompassing MAPT at chromosome 17q21. 3 is associated with developmental delay and learning disability.
    Shaw-Smith C, et al.
    Nature Genetics, 38(9), 1032?1037-1032?1037 (2006)
    The H1c haplotype at the MAPT locus is associated with Alzheimer's disease
    Myers AJ, et al.
    Human Molecular Genetics, 14(16), 2399-2404 (2005)
    Linkage disequilibrium and association of MAPT H1 in Parkinson disease
    Skipper L, et al.
    American Journal of Human Genetics, 75(4), 669-677 (2004)

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