SAB4700088
Monoclonal Anti-CD8-PE antibody produced in mouse
clone MEM-31, purified immunoglobulin, buffered aqueous solution
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.44
Pricing and availability is not currently available.
biological source
mouse
Quality Level
conjugate
phycoerythrin (R-PE) conjugate
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
MEM-31, monoclonal
form
buffered aqueous solution
species reactivity
human
technique(s)
flow cytometry: suitable
isotype
IgG2a
Related Categories
1 of 4
This Item | 551260 | 777846 | 1.07293 |
|---|---|---|---|
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| mp >252 °C (dec.) (lit.) | mp 237 °C (lit.) | mp 124-128 °C | mp 107-109 °C |
| functional group sulfonic acid | functional group carboxylic acid | functional group - | functional group - |
General description
CD8 (cluster of differentiation 8), is a dimeric protein, encoded by the CD8A gene mapped to human chromosome 2p12. Human soluble CD8 (sCD8) is produced by activated CD8+ T lymphocytes.
Immunogen
Crude thymus membrane fraction
Application
The reagent is designed for Flow Cytometry analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 1e6 cells in a suspension. The content of a vial (2 mL) is sufficient for 100 tests.
Biochem/physiol Actions
CD8 (cluster of differentiation 8) acts as a vital co-receptor of cytotoxic T cells. Mutation in the gene has been associated with the development of respiratory infections. Soluble CD8 plays a major role in regulation of soluble human leucocyte antigen I (sHLA-I) mediated transfusion-related immunomodulation (TRIM). Elevated levels of sCD8 has been observed in polytransfused patients suffering from human immunodeficiency virus-negative haemophilia and β-thalassaemia major.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Solution in phosphate buffered saline containing 15 mM sodium azide and 0.2% high-grade protease free BSA as a stabilizing agent.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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