SAB5700493

Anti-Phospho-SRF-S103 antibody produced in rabbit

• Synonym(s): MCM1, SRF
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: 51
• species reactivity: rat, human, mouse
• concentration: 1.03 mg/ml
• technique(s): immunohistochemistry: 1:50-1:100; western blot: 1:500-1:2000
• UniProt accession no.: P11831
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pSer103)
• Gene Information: human ... SRF(6722)

Description

General description

This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). Two transcript variants encoding different isoforms have been found for this gene.

Immunogen

A synthetic phosphorylated peptide around S103 of human SRF (NP_003122.1).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable