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SAB5700630

Sigma-Aldrich

Anti-Caspase 9 antibody produced in rabbit

Synonym(s):

APAF-3, APAF3, CASP9, Caspase 9, ICE-LAP6, MCH6, PPP1R56, casp9, caspase-9

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

17
 30
 36
 46

species reactivity

mouse, rat, human

concentration

0.56mg/ml

technique(s)

immunofluorescence: 1:50-1:200
immunohistochemistry: 1:50-1:200
western blot: 1:500-1:2000

General description

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-98 of human Caspase-9 (NP_001220.2).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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