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SAB5700630

Anti-Caspase 9 antibody produced in rabbit

Name: Anti-Caspase 9 antibody produced in rabbit
Brand: SIGMA

Synonym(s):

APAF-3, APAF3, CASP9, Caspase 9, ICE-LAP6, MCH6, PPP1R56, casp9, caspase-9

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About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

Pricing and availability is not currently available.

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

17
30
36
46

species reactivity

mouse, rat, human

concentration

0.56mg/ml

technique(s)

immunofluorescence: 1:50-1:200
immunohistochemistry: 1:50-1:200
western blot: 1:500-1:2000

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This Item	06536	C80687	C80857
8.02505 trans-Cinnamaldehyde	06536 trans-Cinnamaldehyde	C80687 trans-Cinnamaldehyde	C80857 trans-Cinnamic acid
assay ≥98.0% (GC)	assay ≥95.0% (GC)	assay 97%	assay ≥99%
Quality Level 200	Quality Level 100	Quality Level 100	Quality Level 100
density 1.05 g/cm³ at 20 °C	density 1.05 g/mL at 25 °C (lit.)	density 1.05 g/mL at 25 °C (lit.)	density -
storage temp. 2-30°C	storage temp. 2-8°C	storage temp. -	storage temp. -
form liquid	form -	form liquid	form crystals
mp -8 °C	mp −9-−4 °C (lit.)	mp −9-−4 °C (lit.)	mp 132-135 °C (lit.)

General description

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-98 of human Caspase-9 (NP_001220.2).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Enantioselective Brønsted base catalysis with chiral cyclopropenimines.

Jeffrey S Bandar et al.

Journal of the American Chemical Society, 134(12), 5552-5555 (2012-03-16)

Cyclopropenimines are shown to be a highly effective new class of enantioselective Brønsted base catalysts. A chiral 2,3-bis(dialkylamino)cyclopropenimine catalyzes the rapid Michael reaction of a glycine imine substrate with high levels of enantioselectivity. A preparative scale reaction to deliver 25

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