SAB5702153
Anti-JNK3 Antibody, clone 2O10P2, Rabbit Monoclonal
Synonym(s):
JNK3,JNK3A,PRKM10,SAPK1b,p493F12,p54bSAPK,MAPK10
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.46
biological source
rabbit
Quality Level
material
colorless
clone
2O10P2, monoclonal
form
liquid
mol wt
53 kDa
species reactivity
rat, rat, human
concentration
0.25 mg/mL
technique(s)
western blot: 1:500 - 1:2000
color
colorless
General description
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as integration points for multiple biochemical signals and are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development. This kinase is specifically expressed in a subset of neurons in the nervous system and is activated by threonine and tyrosine phosphorylation. Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2015]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 350-450 of human JNK3 (P53779).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Application
WB
Storage Class
10 - Combustible liquids
wgk_germany
WGK 1
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