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SAB5702382

Sigma-Aldrich

Anti-Integrin linked ILK Antibody, clone 5R10U3, Rabbit Monoclonal

Synonym(s):

HEL-S-28, ILK-1, ILK-2, P59, p59ILK

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46

biological source

rabbit

Quality Level

material

colorless

clone

5R10U3, monoclonal

form

liquid

mol wt

49 kDa

species reactivity

human, rat, rat

concentration

0.40 mg/mL

technique(s)

western blot: 1:500 - 1:2000

color

colorless

General description

This gene encodes a protein with a kinase-like domain and four ankyrin-like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin-mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition, and over-expression of this gene is implicated in tumor growth and metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 350-452 of human Integrin linked ILK (Q13418).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1


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