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SAB5702612

Sigma-Aldrich

Anti-Complement factor H Antibody, clone 10M8Q5, Rabbit Monoclonal

Synonym(s):

AHUS1, AMBP1, ARMD4, ARMS1, CFHL3, FH, FHL1, HF, HF1, HF2, HUS

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46

Pricing and availability is not currently available.

biological source

rabbit

Quality Level

material

colorless

clone

10M8Q5, monoclonal

form

liquid

mol wt

160 kDa

species reactivity

human

concentration

0.37 mg/mL

technique(s)

western blot: 1:500 - 1:2000

color

colorless

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This Item
935093935107935115
concentration

100 mg/mL in toluene

concentration

100 mg/mL in toluene

concentration

100 mg/mL in toluene

concentration

100 mg/mL (in toluene)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

form

liquid

form

liquid

form

liquid

form

liquid

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

description

>6 peak/valley ratio

description

λmax > 5 peak/valley ratio

description

> 3 peak/valley ratio

description

> 2 (peak/valley ratio)

particle size

<15 nm (Nanoparticle)

particle size

<15 nm (Nanoparticle)

particle size

<15 nm

particle size

<15 nm (nanoparticle)

General description

This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Oct 2011]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 100-200 of human Complement factor H (P08603).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1


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