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SAB5702764

Sigma-Aldrich

Anti-GRIK2 Antibody, clone 4B4L9, Rabbit Monoclonal

Synonym(s):

EAA4, GLR6, GLUK6, GLUR6, GluK2, MRT6

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46
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biological source

rabbit

Quality Level

material

colorless

clone

4B4L9, monoclonal

form

liquid

mol wt

100 kDa

species reactivity

rat, rat, human

concentration

0.41 mg/mL

technique(s)

immunohistochemistry: 1:50 - 1:200
western blot: 1:500 - 1:2000

color

colorless

General description

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation. [provided by RefSeq, Jul 2008]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 50-150 of human GRIK2 (Q13002).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB, IHC

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1


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