SAB5702764
Anti-GRIK2 Antibody, clone 4B4L9, Rabbit Monoclonal
Synonym(s):
EAA4, GLR6, GLUK6, GLUR6, GluK2, MRT6
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.46
biological source
rabbit
Quality Level
material
colorless
clone
4B4L9, monoclonal
form
liquid
mol wt
100 kDa
species reactivity
rat, rat, human
concentration
0.41 mg/mL
technique(s)
immunohistochemistry: 1:50 - 1:200
western blot: 1:500 - 1:2000
color
colorless
General description
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation. [provided by RefSeq, Jul 2008]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human GRIK2 (Q13002).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Application
WB, IHC
Storage Class
10 - Combustible liquids
wgk_germany
WGK 1
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