SBR00119

Sarecycline Hydrochloride

• Synonym(s): P-005672 HCl, P005672 HCl
• Empirical Formula (Hill Notation): C₂₄H₃₀ClN₃O₈
• CAS Number: 1035979-44-2
• Molecular Weight: 523.96
• UNSPSC Code: 51101500

Properties

• storage condition: under inert gas
• Quality Level: 100
• antibiotic activity spectrum: Gram-negative bacteria; Gram-positive bacteria
• mode of action: protein synthesis | inhibits
• shipped in: ambient
• storage temp.: 2-8°C
• SMILES string: CN(C)[C@H]1[C@H]2C[C@H]3CC4=C(C=CC(=C4C(=C3C(=O)[C@@]2(C(=C(C1=O)C(=O)N)O)O)O)O)CN(C)OC.Cl
• InChI: 1S/C24H29N3O8.ClH/c1-26(2)18-13-8-11-7-12-10(9-27(3)35-4)5-6-14(28)16(12)19(29)15(11)21(31)24(13,34)22(32)17(20(18)30)23(25)33;/h5-6,11,13,18,28-29,32,34H,7-9H2,1-4H3,(H2,25,33);1H/t11-,13-,18-,24-;/m0./s1
• InChI key: JGPBDCKZLBSHOI-FIPJBXKNSA-N

Description

General description

Sarecycline Hydrochloride is an antibioitc which belongs to the class of couponds know as tetracycline antibiotics. It is a modified derivative of naturally occurring tetracyclines. Sarecycline Hydrochloride is active against a wide range of Gram-positive and Gram-negative bacteria,

Biochem/physiol Actions

Sarecycline Hydrochloride iinhibits bacterial protein synthesis by binding to the 30S subunit of the bacterial ribosome. Specifically, it binds to the A site of the ribosome and blocks the attachment of aminoacyl-tRNA molecules to the ribosome, which is necessary for the addition of new amino acids to the growing polypeptide chain. This ultimately leads to the inhibition of bacterial protein synthesis and reduction in bacteria that are associated with acne.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable