SML0321

Cyamemazine

≥98% (HPLC)

• Synonym(s): 10-[3-(Dimethylamino)-2-methylpropyl]-10H-phenothiazine-2-carbonitrile, 7204 R. E., 7204 RP, Ciamatil, Cianatil, Cyamemazin, R.P. 7204, TH 2602
• Empirical Formula (Hill Notation): C₁₉H₂₁N₃S
• CAS Number: 3546-03-0
• Molecular Weight: 323.46
• EC Number: 222-594-2
• MDL number: MFCD00868180
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825326
• NACRES: NA.77

Properties

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• color: light yellow to yellow-green
• solubility: DMSO: ≥5 mg/mL
• storage temp.: 2-8°C
• SMILES string: CC(CN(C)C)CN1c2ccccc2Sc3ccc(cc13)C#N
• InChI: 1S/C19H21N3S/c1-14(12-21(2)3)13-22-16-6-4-5-7-18(16)23-19-9-8-15(11-20)10-17(19)22/h4-10,14H,12-13H2,1-3H3
• InChI key: SLFGIOIONGJGRT-UHFFFAOYSA-N

Description

Application

Cyamemazine has been used as an internal standard and antipsychotic drug to spike plasma samples in mass spectrometry studies. It has also been used as an analytical standard in gas chromatography-tandem mass spectroscopic (GC-MS/MS) analysis.

Biochem/physiol Actions

Cyamemazine belongs to the class of phenothiazine drugs. It is known to treat severe depression, schizophrenia and bipolar disorder.

Cyamemazine is a potent antagonist of 5-HT2C and 5-HT3 receptors with antipsychotic and anxiolytic properties.

Cyamemazine is a potent antagonist of 5-HT2C and 5-HT3 receptors.

Safety Information

• pictograms: GHS09
• signalword: Warning
• hcodes: H410
• pcodes: P273 - P391 - P501
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable