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SML1322

Sigma-Aldrich

Ipamorelin acetate

≥98%

Synonym(s):

2-Methylalanyl-L-histidyl-3-(2-naphthalenyl)-D-alanyl-D-phenylalanyl-L-lysinamide acetate, Aib-His-D-2-Nal-D-Phe-Lys-NH2 acetate, NNC 26-0161 acetate;

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About This Item

Empirical Formula (Hill Notation):
C38H49N9O5 · xC2H4O2
CAS Number:
Molecular Weight:
711.85 (free base basis)
UNSPSC Code:
51111800
NACRES:
NA.77

Pricing and availability is not currently available.

Quality Level

assay

≥98%

form

powder

color

white to beige

solubility

H2O: 20 mg/L, clear

shipped in

wet ice

storage temp.

−20°C

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This Item
5171278.0352513259
Quality Level

200

Quality Level

100

Quality Level

200

Quality Level

100

assay

99%

assay

≥99%

assay

≥99.0% (GC)

assay

≥99.0% (GC)

form

liquid

form

liquid

form

liquid

form

-

bp

90 °C (lit.)

bp

90 °C (lit.)

bp

90 °C/1016 hPa

bp

90 °C (lit.)

density

1.069 g/mL at 25 °C (lit.)

density

1.069 g/mL at 25 °C (lit.)

density

1.07 g/cm3 at 20 °C

density

1.069 g/mL at 25 °C (lit.)

mp

2-4 °C (lit.)

mp

2-4 °C (lit.)

mp

0.5-4.7 °C

mp

2-4 °C (lit.)

Biochem/physiol Actions

Ipamorelin is a selective growth hormone secretagogue and agonist of the ghrelin receptor that selectively stimulates the ghrelin receptor and causes growth hormone release. The potency and efficacy of ipamorelin are similar to GHRP-6 but without increase plasma levels of ACTH or cortisol. Ipamorelin appears to enter the central nervous system and to activate GRLN receptors in the spinal cord.
Ipamorelin is a selective growth hormone secretagogue and agonist of the ghrelin receptor.
Ipamorelin is known to be useful in reducing the symptoms of postoperative ileus is a gastrointestinal dysfunction arising due to abdominal surgery. Symptoms include abdominal distention, vomiting, nausea, constipation and anorexia.[1]

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Direct synthesis of dimethyl carbonate from carbon dioxide and methanol catalyzed by base.
Fang S and Fujimoto K.
Applied Catalysis A: General, 142(1), L1-L3 (1996)
Thermodynamic Properties of Dimethyl Carbonatea).
Zhou Y, et al.
Journal of Physical and Chemical Reference Data, 40(4), 043106-043106 (2011)
Jana Engeldinger et al.
Physical chemistry chemical physics : PCCP, 14(7), 2183-2191 (2011-11-18)
The simultaneous combination of steady state isotopic transient kinetic analysis (SSITKA) with diffuse reflectance Fourier transform spectroscopy (DRIFTS) and mass spectrometric (MS) analysis was applied to study the oxidative carbonylation of methanol (MeOH) to dimethyl carbonate (DMC) on a CuY
Catalysis in the production and reactions of dimethyl carbonate, an environmentally benign building block.
Ono Y.
Applied Catalysis A: General, 155(2), 133-166 (1997)
Liping Zhang et al.
Bioresource technology, 101(21), 8144-8150 (2010-07-02)
The transesterification of palm oil with dimethyl carbonate (DMC) for preparing biodiesel has been studied in solvent-free system at the catalysis of potassium hydroxide (KOH) as heterogeneous catalyst. Fatty acid methyl esters (FAMEs) were analyzed by GC with internal standard

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