SML2341

Nω-Propyl-L-Arginine hydrochloride

≥98% (HPLC)

• Synonym(s): L-NPA, N(ω)-Propyl-L-arginine, N(w)-Propyl-L-arginine, N-ω-Propyl-L-arginine, N-Omega-propyl-L-Arginine, N5-[Imino(propylamino)methyl]-L-ornithine, NG-Propyl-L-arginine, NPA, NPLA, Nomega-Propyl-L-Arginine, PLA, p-ARG
• Empirical Formula (Hill Notation): C₉H₂₀N₄O₂ · xHCl
• CAS Number: 137361-05-8
• Molecular Weight: 216.28 (free base basis)
• MDL number: MFCD01320455
• UNSPSC Code: 12352209

Properties

• assay: ≥98% (HPLC)
• form: film
• storage condition: desiccated
• color: colorless
• solubility: H₂O: 2 mg/mL, clear
• storage temp.: −20°C
• SMILES string: CCCNC(NCCC[C@H](N)C(O)=O)=N
• InChI: 1S/C9H20N4O2/c1-2-5-12-9(11)13-6-3-4-7(10)8(14)15/h7H,2-6,10H2,1H3,(H,14,15)(H3,11,12,13)/t7-/m0/s1
• InChI key: AOMXURITGZJPKB-ZETCQYMHSA-N

Description

Biochem/physiol Actions

Nω-Propyl-L-arginine (NPA; NPLA; p-ARG; L-PNA) is a substrate-competitive, reversible, potent and selective neuronal nitric oxide synthase (nNOS; bNOS) inhibitor (Ki = 57 nM/bovine nNOS, 8.5 μM/bovine eNOS, 180 μM/murine iNOS) widely used for probing nNOS-dependent physiological and pathological processes both in cultures and in animals in vivo.

Substrate-competitive, reversible, potent and selective neuronal nitric oxide synthase (nNOS; bNOS) inhibitor with in vitro and in vivo efficacy.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable