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SML2727

Sigma-Aldrich

BAY 41-8543

≥98% (HPLC)

Synonym(s):

2-[1-[(2-Fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-(4-morpholinyl)-4,6-pyrimidinediamine, BAY41-8543

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About This Item

Empirical Formula (Hill Notation):
C21H21FN8O
CAS Number:
Molecular Weight:
420.44
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.77

Pricing and availability is not currently available.

Quality Level

assay

≥98% (HPLC)

form

powder

color

white to very dark brown

solubility

DMSO: 2 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

Fc1c(cccc1)C[n]2nc(c5c2nccc5)c3nc(c(c(n3)N)N4CCOCC4)N

InChI

1S/C21H21FN8O/c22-15-6-2-1-4-13(15)12-30-21-14(5-3-7-25-21)16(28-30)20-26-18(23)17(19(24)27-20)29-8-10-31-11-9-29/h1-7H,8-12H2,(H4,23,24,26,27)

InChI key

AQYFUZRYBJBAGZ-UHFFFAOYSA-N

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Show Differences

1 of 4

This Item
C-12500C-14059C-12575
morphology

(smooth muscle)

morphology

(smooth muscle)

morphology

(smooth muscle)

morphology

(smooth muscle)

biological source

human umbilical cord artery

biological source

human umbilical cord artery

biological source

human uterus (myometrium)

biological source

human uterus (myometrium)

storage temp.

−20°C

storage temp.

−196°C

storage temp.

−20°C

storage temp.

−196°C

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

packaging

pkg of 1,000,000 cells

packaging

pkg of 500,000 cells

packaging

pkg of 1,000,000 cells

packaging

pkg of 500,000 cells

application(s)

cell analysis (DNA, RNA, and protein)

application(s)

-

application(s)

cell analysis (DNA, RNA, and protein)

application(s)

-

Biochem/physiol Actions

BAY 41-8543 is a stimulator of soluble Guanylyl cyclase (guanylate cyclase, sGC), the primary cellular receptor for nitric oxide (NO).
Guanylyl cyclase (sGC) stimulator

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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