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SML3485

Sigma-Aldrich

PFI-7 hydrochloride

≥98% (HPLC)

Synonym(s):

N-((1s,4s)-4-(1H-Benzo[d]imidazol-2-yl)cyclohexyl)-2-((1H-indol-2-yl)methylamino)acetamide hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C24H27N5O · xHCl
Molecular Weight:
401.50 (free base basis)
UNSPSC Code:
12352200
NACRES:
NA.28

Pricing and availability is not currently available.

Quality Level

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

H2O: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

O=C(CNCC1=CC2=C(N1)C=CC=C2)N[C@@H]3CC[C@@H](CC3)C4=NC5=C(N4)C=CC=C5

InChI key

HLHNFJNSQZZUNW-MAEOIBBWSA-N

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grade

certified reference material

grade

certified reference material

grade

certified reference material

grade

certified reference material

format

matrix material

format

matrix material

format

matrix material

format

matrix material

packaging

pkg of disk

packaging

pkg of disk

packaging

pkg of disk

packaging

pkg of disk

technique(s)

X-ray spectroscopy: suitable

technique(s)

X-ray spectroscopy: suitable, optical emission spectroscopy (OES): suitable

technique(s)

X-ray spectroscopy: suitable, optical emission spectroscopy (OES): suitable

technique(s)

X-ray spectroscopy: suitable, optical emission spectroscopy (OES): suitable

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

Biochem/physiol Actions

PFI-7 is a high affinity E3 ligase GID4 probe (KD = 0.08 μM by SPR) that competes against cellular degrons for full-length GID4 binding with high potency (EC50 = 0.6 μM by cell-based NanoBRET).

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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