SML3514

Corylin

≥98% (HPLC)

• Synonym(s): 3-(2,2-Dimethyl-2H-1-benzopyran-6-yl)-7-hydroxy-4H-1-benzopyran-4-one
• Empirical Formula (Hill Notation): C₂₀H₁₆O₄
• CAS Number: 53947-92-5
• Molecular Weight: 320.34
• MDL number: MFCD20260784
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: O=C1C2=CC=C(C=C2OC=C1C3=CC4=C(C=C3)OC(C)(C)C=C4)O
• InChI key: PWAACAMQKVIVPZ-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Corylin is a flavonoid isolated from fruit and seed of medical herb Psoralea corylifolia that extend the replicative lifespan in yeast by targeting the Gtr1 protein. Also, Corylin extends lifespan in mice fed a high-fat diet. Corylin exhibits numerous pharmacological effects such as antioxidant properties, anti-inflammatory effects, osteoblastic proliferation-stimulating activity, insulin resistance amelioration.

Extend the replicative lifespan in yeast by targeting the Gtr1 protein

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable