SRP0347
EphB4 active human
recombinant, expressed in baculovirus infected Sf9 cells
Synonym(s):
EPH receptor B4, HTK, MYK1, TYRO11
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About This Item
General description
Human EPHB4 ( GenBank Accession No. NM_004444), amino acids 563-987 with N-terminal His tag, MW=50 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
Application
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Unit Definition
One unit is defined as the amount of enzyme that will transfer 1 nmol phosphate to tyrosine substrate per minute at pH 7.4 and 30° C.
Storage Class
10 - Combustible liquids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Thomas Bruhl et al.
Circulation research, 94(6), 743-751 (2004-02-07)
Homeobox genes (Hox) encode for transcription factors, which regulate cell proliferation and migration and play an important role in the development of the cardiovascular system during embryogenesis. In this study, we investigated the role of HoxA9 for endothelial cell migration
Yusuke Takahashi et al.
Anticancer research, 34(6), 2913-2918 (2014-06-13)
Signaling induced by binding of erythropoietin-producing hepatoma-amplified sequence (EPH) receptors to their cell-surface ephrin ligands is implicated in hematopoiesis and growth of various cancer cells. However, the roles of EPH-ephrin signaling in leukemia have not been elucidated. We investigated the
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