SRP2002

TFIIA-p12 human

recombinant, expressed in E. coli, ≥80% (SDS-PAGE)

• Synonym(s): HsT18745, TF2A2, TFIIA
• UNSPSC Code: 12352202
• NACRES: NA.26

Properties

• biological source: human
• recombinant: expressed in E. coli
• assay: ≥80% (SDS-PAGE)
• form: frozen liquid
• mol wt: ~14.5 kDa
• packaging: pkg of 10 μg
• storage condition: avoid repeated freeze/thaw cycles
• concentration: 300 μg/mL
• color: clear colorless
• NCBI accession no.: NM_004492
• UniProt accession no.: P52657
• shipped in: dry ice
• storage temp.: −70°C
• Gene Information: human ... GTF2A2(2958)

Description

Biochem/physiol Actions

p12 is a small subunit ( γ ) of the transcription factor IIA and has been shown to be required for both basal and activated transcription. Recombinant p12, along with two other subunits ( α and β ) can potentiate transcriptional activation, whereas p12 along with β subunit is able to function in an anti-repression for reconstitued TFIIA, containing all three subunits.

Physical form

Clear and colorless frozen liquid solution

Preparation Note

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable